Hypertensive Drugs Flashcards
Clonidine
Alpha 2 agonist
Opiod withrawal
SE: Rebound HTN
Methyldopa
Alpha 2 agonist
Pre eclampsia
SE:
Sedation
Hemolytic anemia
Reserpine
IRREVERSIBLY blocks VMAT
GUANETHIDINE
Inhibit vesicular release of NE
PRAZOSIN
SImD:
TAMSULOSIN
ALPHA 1 SELECTIVE ADRENERGIC BLOCKER/ ANTAGONIST
BPH
PROPANOLOL
Beta non selective
Reduce RENIN
Mingraine
SE:
ED, AV
Carve, labe. Alpha and beta
Pheochromocytoma
PHENOXYBENZAMINE
PHENTOLAMINE
LABETALOL
“LAB PHE PHE”
HYDRALAZINE
Intracellular Ca++
HF in combi ISDN
PRE ECLAMPSIA
SE
MI, DI-SLE
MINOXIDIL
Open k channels in Smooth muscle > hyperpolarization
ALOPECIA
SE
RT, Na ret
Use with diuretic
VERAPAMIL
Diltiazem- for reynauds
ND- CCB
Cardiac> vascular
block Voltage gated LType ca channel
SVT
SE: pretibial edema
Gingival hyperplasia
WOF <3 depression
NIFEDIPINE
D- CCB
vascular> cardiac
Volatage gated L type Ca channel
NITROPRUSSIDE
Increase NO> inc cGMP
SE:
Cyanide toxicity
LIGHT SENSITIVE
IV INFUSION
FENOLFOPAM
D1 agonist
Ateriolar vasodiltion
Increase renal blood flow
HYPERTENSIVE EMERGENCY
CAPTOPRIL
ACE INHIBITOR
ACE> angeotensin 2
SE:
Angioedena
Taste changes
Slows ventricular remodelling
Delays diabetic retinopathy-
decrease albumin excretion
Teratogenic: skull hypoplasia
Short half life
WOF renal stenosis
LOSARTAN
ARB At1 receptor block
SE
HYPOGLYCEMIA
ANEMIA
LESS COUGH
