Hypertensive Disorders Of Pregnancy Flashcards
Diastolic range of mild hypertension
90-100
Diastolic range of moderate hypertension
100-110
Diastolic range of severe hypertension
110+
Maternal factors that carry the risk of developing pre-eclampsia
Previous pre eclampsia, pre existing medical disorders, autoimmune diseases and a raised BP at first visit
Screening tests of Pre-eclampsia
Uterine artery Doppler studies, PIGF (placental growth factor) and Plasma PAPP-A
According to the Fetal med foundation, risk for pre-eclampsia can be derived from a combination of bio markers, this is by calculating the PI (mean uterine pulsatility index) what is the formula
PSV-EDV/TAV
Peak systolic velocity -End diastolic velocity / by Timed average velocity
Pregnant women at risk of pre-eclampsia are advised to take what and when
Prophylactic Low dose aspirin (75-150mg) daily. From 12 weeks until birth.
while the majority of women are asymptomatic, what’s the symptoms
Severe headache, blurred vision, severe pain just below the ribs, vomiting, and a sudden swelling of the limbs
Pre eclampsia diagnostic BP
> 140/90mmHg
HELLP syndrome is a fever form of pre-eclampsia, what does the acronym stand for
Hemolysis, elevated liver enzymes, and low platelet count
Management of HELLP:
Stabilizing mother, transfusion of blood components, and pregnancy termination. In that order
A woman with BP >=160/110mmHg requires urgent treatment why
Significant risk of intracranial hemorrhage
What is the aim of maternal treatment in pre-eclampsia
Stabilize BP and prevent convulsions
Is there a cure for pre-eclampsia?
No. Just to terminate the pregnancy
Diagnostic investigations of pre-eclampsia
CBC, Renal and liver function tests. Ultrasound for fetal growth. And Umbilical artery doppler
Antihypertensive medication of choice
Labetalol.
If Labetalol is not suitable?
Oral nifedipine
If Labetalol and Oral Nifedipine aren’t suitable?
Methyl Dopa
What antihypertensive medication do we give in Severe PET
IV hydralazine
When treating Hypertension, we avoid giving two medications, what are they
Diuretics and ACE inhibitors
We consider giving what to women with Severe PET if they are deteriorating in their labs or planning to give birth in 24 hours
IV magnesium sulphate
What exactly are our indictions for delivery in pre-eclampsia?
> 37 weeks gestation, uncontrolled BP despite trying 3 or more antihypertensives. And or progressive deterioration in their labs
If a woman has taken Methyl Dopa, why do we stop it 2 days after birth?
Its side effects include sedation and depression.
What is Eclampsia
The onset of seizures in a woman with pre eclampsia