Hypertensive Disorders in Pregnancy Flashcards
Leading cause of maternal death
5-10% of pregnancies
Hypertensive disorders
Classifications
Chronic
Gestational
Superimposed
Pre-eclampsia/ eclampsia
Chronic
8% of pregnancies
>140/90 before 20 weeks or after 12 weeks
Gestational
> 140/90 after 20 weeks of gestation
absence of proteinuria
Superimposed
Chronic and worsening developing new-onset proteinuria after 20 weeks
Pre-eclampsia
2-8% incidence
>140/90 mmHg after 20 weeks of gestation
proteinuria
Risk factors
Family history
Nulliparity
Genetic predisposition
Multifetal pregnancy
>35 years of age
IVF
Pre existing Hypertention
Diabetes
Chronic kidney disease
Obesity
Hmol
Trisomy 13
Negative risk factors
Maternal smoking
Prolonged sexual cohabitation
What does shallow placentation cause?
Reduced placental perfusion
Intrauterine growth restriction
Reduced fetal oxygen and nutrient intake
Which clinical manifestations could indicate preeclampsia?
Elevated AST levels
Seeing circles around lights
Urinating very little
Which manifestations reflect increased capillary permeability in preeclampsia?
Generalized edema
Fluid in the lungs
Protein in the urine
Which vascular manifestations occur in preeclampsia?
Cerebral edema
Damaged capillaries and leakage
Coagulation abnormalities
Diagnosis Pre eclampsia
> 140/90 mm Hg on two separate occasions at
least 4 hours apart
Proteinuria, Protein > 300 mg (PCR) > 0.3 g
Diagnosis Severe Preeclampsia
> 160/110 mm Hg
Platelet < 100,000/mm3
Serum creatinine increase > 1.1 mg/dL
Pulmonary edema
treatment for preeclampsia
Delivery of the placenta
Management
Prenatal care
BP monitoring
Managing complications
Timely delivery
corticosteroids
Pp monitoring
Surveillance
Non stress test
Ultrasound
McDonalds measurement
How long should the maternal blood pressure be monitored postpartum?
72 hours
Eclampsia
Preeclampsia and grand mal seizure activity
Symptoms
Frontal headaches
Blurred vision
Photophobia
Epigastric pain
Altered mental status
NONE
Variants
Hemolysis
Elevated
Liver enzymes
Low
Platelet count
Medications to manage pre eclampsia
Calcium channel blockers
Beta-blockers
Nonsteroidal anti-inflammatory drugs
Antiadrenergic agents
Diuretic
Magnesium sulfate,
prevent seizures
MS antidote
Calcium gluconate