Hypertension Pales CIS Flashcards
Definition of Htn
Normal:
Systolic
What are the contributing (risk) factors for developing essential HTN?
Genetic predisposition Abdominal Obesity Salt intake Alcohol intake Age
HTN is a risk factor for:
Stroke Myocardial Infarction Heart Failure ESRD Atrial Fibrillation Aortic Dissection PVD
older patients with HTN?
lder patients have atherosclerosis in larger vessels, aorta
high systolic and lower diastolic
What is the likely mechanism of this patient’s blood pressure elevation?
vasoconstriction of capillaries, or vasospasm
physical activity
Modification: engage in regular aerobic physical activity such as brisk walking 30 min every day
Approximate systolic bp reduction range: 4 to 9 mmHg
Weight reduction
Modification: maintain normal body weight
Approximate systolic bp reduction range: 5-20 mmHg per 10kg of weight loss
adopt a dash eating plan
Modification: consume a diet rich in fruits beggies and low fat dairy products with a reduced content of saturated and total fat
Approximate systolic bp reduction range: 8 to 14 mmHg
dietary sodium reduction
Modification: Reuce dietary sodium intake to no more than 100meq/day (2.4 g sodium or 6 g sodium cholride
Approximate systolic bp reduction range:2 to 8 mmHg
Moderation of alcohol consumption
Modification: limit consumption to no more than 2 drinks per day in most men and no more than 1 drink per day in women and ligther weight persons
Approximate systolic bp reduction range: 2 to 4 mmHg
Initial Recommended HTN treatment for Non-Black population
ACE Inhibitors
ARB
CCB
Thiazide diuretics
Initial Recommended HTN treatment for Black population
CCB
Thiazide diuretics
When should we suspect secondary HTN?
Compelling finding on initial evaluation
Hard to control HTN (either new onset or well controlled HTN becoming hard to control)
Atypical age of diagnosis (less than 30)
Absence predisposing factors
Diagnosis of Renovascular Hypertension
- Captopril Test (reactive rise in renin and large fall in BP after administration)
- DSA
- MRI –angiography
- Arteriography
- Renal vein renin ratio (ratio of 1.5 or greater)
2 main cuases of renovascular hypertension
atherosclerosis
fibromuscular dysplasia
Atherosclerosis over view
Age - >50 sex - male bilaterality33% - progressive - +++ response to angioplasty - + associated risks, tobacco, lipids, diabetes, etc - +++
fibromuscular dysplasia overview
Age -
3 types of renovasuclar htn
Unilateral
bilateral
one kidney
Unilateral renovascular htn
decreases intravascular volume
more renin mediated than the others
bp usually falls with ACEI
Bilateral renovasuclar htn
increase intrabascular volume
renin mediation is more varied
ace response unpredicatlbe and may worsen htn
One kidney renovascular htn
increased intravascular volume
renin mediation is more varied
ace response unpredicatable andy may worsen htn
graves disease tests
tsh should be low, t3 would be high and antibodies will be high
meds for graves (hyperthyroidism)
beta blockers for htn
hypertensive urgency
A systolic BP > 180 or a diastolic BP > 130 and NO evidence of end organ damage.
hypertensive emergency
May occur at any BP, but involves ACUTE DAMAGE to at least one organ system.
Signs of Target Organ Involvement Acute and Chronic
cardiovascular
MI (A), Angina (A), Aortic dissection (A), Aneurysmal dilatation of large vessels (C), LVH (C),
CHF (A)
Signs of Target Organ Involvement Acute and Chronic
CNS
Cerebral edema (A), Altered mental status (A), Bleed (A), Stroke (A) or TIA (A)
Signs of Target Organ Involvement Acute and Chronic
renal
Hematuria (C), Proteinuria (C), ARF (A)
Signs of Target Organ Involvement Acute and Chronic
ophthalmologic
Retinal hemorrhages or exudates (A or C), Papilledema (A)
A-V nicking (C)
primary hyperaldosteronism
cons disease
- Located in adrenal gland without exogenous stimulus.
2. Elevated aldosterone and low renin levels
Primary hyperaldosteronism types
- Aldosterone producing adenoma
- Idiopathic Hyperaldosteronism
- Bilateral adrenal hyperplasia
- Aldosterone producing Ca
- Aldosterone producing renin-responsive adenoma
- Ectopic aldosterone producing tumor
- Dexamathasone suppressible hyperaldosteronism
Secondary hyperaldosteronism
Elevated aldosterone and elevated renin levels Causes are: 1. Diuretics 2. CHF 3. Cirrhosis 4. Ascites 5.
why are pts with hyperaldosteronism weak
hypokalemia
how do you treat hyperaldosteronism?
aldosterone blockers
spironolactone
secondary hypertension causes
- Sleep apena
- Drug induced causes
- Chronic kidney disease
- Primary aldosteronism
- Renovascular disease
- Steroid therapy or Cushing’s syndrome
- Pheochromocytoma
- Coarctation of the aorta
- Thyroid disease
- Parathyroid disease
- Pain induced
coarctation of aorta
1) Narrowing of medial layer of aorta.
2) Commonly at ligamentum arteriosum.
3) 3 types:
A) Interrupted
B) Preductal
C) Postductal
Diagnosis of Coarctation
- Differences in upper and lower extremities
- Blood Pressure
- systolic hypertension in an infant
- 20mm hg between arms
- Heart Sounds –if isolated a systolic ejection murmur in the aortic outlet and between scapulae.
- Radiology –
- Cardiomegaly
- Rib notching
Suffices
acei
pril