Hypertension In Pregnancy Flashcards
Gestational Hypertension
onset of hypertension w/o proteinuria after 20 wks gestation
Preeclampsia
Occurs 20 wks after a gestation in normotensive pt and has proteinuria
can be mild or serve
Proteinuria
at or above 30 mg (>=1 dipstick)
Eclampsia
Occurrence of seizures or coma in a woman w/ preeclampsia
Chronic HTN
HTN occurs before pregnancy or diagnosis before 20th week or persists more than 6-12 months after post
Preeclampsia superimposed on Chronic HTN
HTN Chronic with new proteinuria or an exacerbation of HTN or Proteinuria, thrombocytopenia or ^ in hepatocellular enzymes
HTN Ranges
Systolic BP > 140 mm Hg
Diastolic > 90 mm Hg
MAP >105 mm Hg
Primigravidas HTN
First pregnancy HTN
More likely
Multiparous HTN
Multiple pregnancies HTN
When does BP return to normal after delivery
1-12 wks
Mild Preeclampsia
BP 140/90
MAP >105
24 hr urine protein
>= 0.3g or 300 mg = +1dipstick
Severe Preeclampsia
BP >= 160/110 mm Hg 2 occasions at least 4 hrs apart
MAP >105
24hr urine protein >2g=2000mg
Risk Factors of Preeclampsia
Chronic Renal disease
Chronic HTN
Family hx of preeclampsia
Multiple gestations
Primigradivity or a new partner
Maternal age
Diabetes
Rh incompatibility
Obesity
Etiology of Preeclampsia
Disruption in Placental perfusions and endothelial cell dysfunction
Consequences of endothelial cell dysfunctions
Vasospasms and decreased organ perfusion
Intravascular coagulation
Increased permeability and capillary leakage
Intravascular coagulation
hemolysis RBC, low platelet counts, DIC, ^ Factor 8 antigen
Vasospasms and decreased organ perfusion
HTN, uteroplacental spasms, HA, blurred vision, hyperreflexia, ^ liver enzymes, NV, epigastric pain
Increased permeability and capillary leakage
Proteinuria, generalized edema, pulmonary edema (dyspnea), hemoconcentration (^ hematocrit)
Effects of Preeclampsia: Placental
Impaired perfusion = IUGR and early aging of the placenta
Effects of Preeclampsia: renal
v GFR, oliguria, ^ excretion of protein, v uric acid clearance, Na+ and H20 retention
Effects of Preeclampsia: Hepatic
v perfusion = hepatic edema and subcapsular hemorrhage, complaint of epigastric pain or RUQ pain
Effects of Preeclampsia: Neurological
Cerebral edema, CNS irritability, Visual disturbances
Effect of Preeclampsia: Laboratory Values
v serum albumin
^ Hct
^ BUN, creatinine, uric acid
Testing for Proteinuria
300 mg/dl >= 1+ on dipstick
At 6 hrs apart or 24 hrs specimen