Hypertension - Aldosterone Antagonists

Question 1

Name 2 examples of aldosterone antagonists

Answer 1

Spironolactone

Eplereonone

Question 2

Where do the aldosterone antagonists work?

Answer 2

In the collecting duct

Question 3

SE of aldosterone antagonists

Answer 3

Hyperkalemia

*Spironolactone causes gynomas

Question 4

When do you start aldosterone antagonists?

Answer 4

Really resistant HTN (that you start working them up for hyperaldosteronism)
CHF, class 3 (you can use a combo dilator for CHF class 3 too)