hypertension Flashcards

1
Q

what is the WHO classification for hypertension

A

140/90 mmHg on at least two readings on separate occasions

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2
Q

vascular changes that occur with hypertension (2)

A
  • Accelerates atherosclerosis
  • Causes thickening of media of muscular arteries
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3
Q

how do kidneys affect hypertension

A

Can cause or result from renal disease

Kidney size often reduced and small vessels show intimal thickening and medial hypertrophy

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4
Q

characteristic features of hypertension

A

Markedly raised diastolic BP (usually over 120mmHg)

Progressive renal disease

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5
Q

8 risk factors for hypertension

A

Family history
Old age
Low birthweight
Male
Afro-Caribbean’s
Unhealthy diet
Lack of physical activity
Obesity

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6
Q

what is essential primary origin hypertension

A

occurs when you have abnormally high blood pressure that’s not the result of a medical condition

90% are this

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7
Q

secondary causes of hypertension (5)

A
  1. renal
  2. endocrine
  3. Coarctation of the aorta
  4. Pre-eclampsia occurring during third trimester of pregnancy
  5. drugs
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8
Q

which endocrine conditions can cause hypertension (3)

A

Conn’s syndrome, acromegaly, Cushing’s syndrome

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9
Q

which drugs can cause hypertension (3)

A

oestrogen-containing oral contraceptives

NSAIDs

vasopressin

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10
Q

is there signs and symptoms for hypertension

A

no most people are asymptomatic
except for in malignant hypertension

may have the occasional headache

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11
Q

what investigations for hypertension

A

blood pressure

tests to asses end organ damage

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12
Q

how to confirm diagnosis if blood pressure is more than 140/90

A

24-hour ambulatory BP monitor (ABPM)
Multiple home BP monitoring (if patient can’t tolerate ABPM)

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13
Q

when is treatment given

A

if ABPM 135/85

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14
Q

what tests can you do to assess end organ damage (5)

A
  • Urinalysis to check kidneys (protein, albumin: creatine ratio and haematuria)
  • ECG/Echo for LV hypertrophy
  • Fundoscopy to assess hypertension retinopathy
  • Bloods
    Serum creatinine
    eGFR
    Glucose – assess diabetes risk
  • Clinical history – previous MI/strokes
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15
Q

what lifestyle changes can you do for hypertension

A

Smoking cessation
Low-fat diet + high consumption of fruit and vegetables
Reduce alcohol and salt intake
Increase exercise
Loss weight is obese

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16
Q

first line drug treatment for hypertension

A

ACE inhibitor or calcium channel blocker

17
Q

second line treatment for hypertension

A

ACE-inhibitor + CCB

18
Q

third line treatment for hypertension

A

ACE-inhibitor + CCB + diuretics

19
Q

fourth line treatment for hypertension

A

ACE-inhibitor + beta blocker

20
Q

what is malignant hypertension

A

Rapid rise in BP leading to vascular damage

21
Q

symptoms of malignant hypertension

A

Headache
Visual disturbance

22
Q

signs of malignant hypertension

A

Severe hypertension
Systolic > 200 mmHg
Diastolic > 130 mmHg

Bilateral renal haemorrhage = exudates = papilloedema

23
Q

complications of maligant hypertension

A

Hypertensive emergencies e.g. acute kidney injury, HF and encephalopathy
`

24
Q

treatment for malignant hypertension

A

Sodium nitroprusside