Hypertension Flashcards
1
Q
Where is renin released from?
A
JGA of kdiney
2
Q
What causes renin release
A
Reduced NA devliery to DCT
Beta adrenergic stimulation
Reduced arterial perfusion
3
Q
What does the RAAS system do
A
Response to low BP
RAISES BP
- Sodium, water retention
4
Q
Action of renin
A
angiotensinogen to AT1
5
Q
Where does ACE act?
A
Lungs
AT1 to AT2
6
Q
Where does AT2 act?
A
Vasoconstriction
NA resorption in kindye
Sympathetic acitvation
Aldosterone release
ADH release from hypothalamus
7
Q
Actions of aldosterone
A
Acts on CD in nephrons
Increase Na/K/ATPase
Increase sodium levels
Excrete potassium
8
Q
Side effects of ACE inhibitors
A
Dry cough
Hyperkalaemia
Renal impairment
Angio-oedema
