Hypertension Flashcards

1
Q

First line treatment in patient age <55 and not of

black African or African– Caribbean family origin / With T2DM

A

ACEi or ARB

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2
Q

First line treatment in patient age >55 / Afro-caribbean

A

CCB

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3
Q

Second line treatment

A

Add ACEi or ARB if already added CCB
Add CCB if already added ACEi or ARB
OR thiazide-like duiretic

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4
Q

Third line treatment

A

ACEi or ARB + CCB + thiazide-like duiretic

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5
Q

Fourth line treatment

A

Confirm resistant hypertension: confirm elevated BP with ABPM or HBPM, check for postural hypotension and discuss adherence.

Consider seeking expert advice or adding a:
• low-dose spironolactone if blood potassium level is ≤4.5 mmol/l
• alpha-blocker or beta-blocker if blood potassium level is >4.5 mmol/l
Seek expert advice if BP is uncontrolled on optimal tolerated doses of 4 drugs

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6
Q

BP target age <80 years:

A
  • Clinic BP <140/90 mmHg

* ABPM/HBPM <135/85 mmHg

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7
Q

BP target age ≥80 years:

A
  • Clinic BP <150/90 mmHg

* ABPM/HBPM <145/85 mmHg

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8
Q

BP target postural hypotension:

A

• Base target on standing BP

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9
Q

BP target frailty or multimorbidity:

A

• Use clinical judgement

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10
Q

Measure standing and sitting BP in people

with:

A
  • type 2 diabetes or
  • symptoms of postural hypotension or
  • aged 80 and over.
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11
Q

In BP under 140/90 mmHg

A

Check BP at least every 5 years and more

often if close to 140/90 mmHg

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12
Q

Treatment for age >80 with clinic BP >150/90 mmHg:

A

• Offer lifestyle advice and consider drug treatment

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13
Q

Treatment for age <80 with target organ damage, CVD, renal disease, diabetes or 10-year CVD risk ≥10% and with clinic BP >150/90 mmHg:

A

• Offer lifestyle advice and discuss starting drug treatment

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14
Q

Treatment for age <60 with 10-year CVD risk <10% and with clinic BP >150/90 mmHg:

A

• Offer lifestyle advice and consider drug treatment

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15
Q

Treatment for age <40 with clinic BP >150/90 mmHg:

A

• Consider specialist evaluation of secondary causes and assessment long term benefits and risks of treatment

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16
Q

Treatment for 150/95 mmHg or more (stage 2)

A

Offer lifestyle advice and drug treatment

Age <40:
• Consider specialist evaluation of secondary causes and assessment long term benefits and risks of treatment

17
Q

ACI Inhibitors list (4)

A

enalapril, lisinopril, perindopril and ramipril.

18
Q

ACI Inhibitors common side effects

A

Persistent dry cough!

headaches, dizziness and a rash.

19
Q

Angiotensin-2 receptor blockers (ARBs) list (5)

A

candesartan, irbesartan, losartan, valsartan and olmesartan.

20
Q

ARB common side effects

A

dizziness, headaches, and cold or flu-like symptoms.

21
Q

Calcium channel blockers (5)

A

amlodipine, felodipine and nifedipine.

also diltiazem and verapamil, are also available.

22
Q

Calcium channel blockers side effects

A

headaches, swollen ankles and constipation.

23
Q

You shouldn’t take … with …

A

grapefruit juice with calcium channel blockers

24
Q

Contraindications to ACI Inhibitors

A

Pregnancy and breast feeding

Angioedema

25
Q

Contraindications to Angiotensin-2 receptor blockers

A

Pregnancy and breast feeding

26
Q

Contraindications to Calcium channel blockers

A

Heart failure

27
Q

Contraindications to thiazide-like diuretics

A

Diabetes; gout; risk of hypokalaemia; systemic lupus erythematosus, addisions

28
Q

thiazide-like diuretics

A

indapamide, bendroflumethiazide

29
Q

thiazide-like diuretics side effects

A

dizziness when standing up, increased thirst, needing to go to the toilet frequently, and a rash.

You might also get low potassium and low sodium after long-term use.

Gout