Hypertension Flashcards
What is the definition of hypertension? (3 points)
- Persistently elevated arterial blood pressure >140/90mmHg
- The BP level that increases the vascular risk in patients sufficient to require intervention
- The threshold at which the benefits of action exceed those of inaction
What is hypertension a risk factor for?
- Development of coronary artery disease
- cerebrovascular disease
- Peripheral vascular disease
- Heart failure
- End stage renal disease
What are the non modifiable risk factors associated with hypertension?
- age
- Gender
- Race
- Genetic factors
What are the modifiable risk factors of hypertension?
- Exercise
- Diet
- Obesity
- alcohol in excess
- Stress
What are the endocrine causes of hypertension?
- Hyperaldosteronism
- Phaeochromocytoma
- Thyroid disorders
- Cushing’s syndrome
What are the vascular causes of hypertension?
coarctation of the aorta
What are the renal causes of hypertension?
- Renal artery stenosis
* Renal parenchymal disease
What drugs can cause hypertension?
- NSAIDs
- Herbal remedies
- Cocaine
- Exogenous steroid use
What are the physical examination components of a systemic hypertension assessment?
- BP readings of both arms, consider ABPM
- Examination of the heart and lungs
- Ausculation for carotid/abdominal/femoral bruit
- Examination of the thyroid gland
- Examination of the abdomen
- Palpation of the lower extremities for oedema and pulses
- Optic fundi examination
- Neurological exam and cognitive status assessment
What investigations should be carried out in the assessment of hypertension?
- Routine metabolic panel and lipids
- Renal function (eGFR and Creatinine)
- FBC
- Urinalysis
- ECG
What investigations should be carried out in the assessment of hypertension?
- Routine metabolic panel and lipids
- Renal function (eGFR and Creatinine)
- FBC
- Urinalysis
- ECG
If you are suspecting a secondary hypertension or if the BP has been hard to control, what extra tests should be carried out?
- Echocardiogram and doppler
- Sleep study (looking for signs of obstructive sleep apnoea)
- Pheochromocytoma screen
- TFTs
- Plasma renin/aldosterone
- Renal artery imaging
What are the lifestyle modifications for the management of systemic hypertension?
- Education
- Sodium reduction
- DASH diet
- Weight loss to a BMI of about 25kg/m^2
- Increased physical activity (150 mins a week)
- Limited alcohol consumption
- Smoking cessation
What are the steps of pharmacological management of hypertension?
- Step 1: CCB (>55/black African) or ACEi/ARB (<55)
- Step 2: ACEi or ARB, and CCB (or switch the new drug out for a thiazide like diuretic)
- Step 3: ACEi/ARB, CCB and thiazide like diuretic or an alpha or beta blocker (depending on potassium level)
What is the pathophysiology of hypertension?