Hypersensitivity types Flashcards
type 1
(IgE, mast cell, eosinophils) allergic conjunctivitis, hay fever, VKC, GPC, AKC (also type IV)
type II
(cytotoxic->ab->ag->complement) ocular cicatricial pemphigoid, Mooren’s
type III
(antibody/antigen complex) Staph marginal, disciform keratitis, subepi infiltrates, Wessely ring, scleritis, phacoanaphylactic endophthalmitis (zonal granuloma)
type IV
(delayed cell mediated, T cell) SJS, phylectenule, AKC (also I), graft rejection, contact dermatitis, interstitial keratitis, granulomatous disease (syphilis, TB, leprosy), acne rosacea, sympathetic ophthalmia
type V
(stimulating ab) Graves, MG
allergic conjunctivitis
I
hay fever
I
VKC
I
GPC
I
AKC
I, IV
ocular cicatricial pemphigoid
II
Mooren’s
II
SJS
IV
Staph marginal
III
Disciform keratitis
III
Subepi infiltrates
III
Wessely ring
III
scleritis
III
phacoanaphylactic endophthalmitis (zonal granuloma)
III
phlyctenule
IV
graft rejection
IV
contact dermatitis
IV
interstitial keratitis
IV
granulomatous disease - syphilis, TB, leprosy
IV
acne rosacea
IV
sympathetic ophthalmia
IV
Graves
V
MG
V