from EBOD Flashcards
signs of keratoconus
Munson’s sign, Fleischer ring and Vogt’s striae
Bowman’s membrane has a thickness of
8-12 microns
Bowman’s membrane - regenerative capacity
not good
The main collagen fibres in the stroma are
I, III, V and VI
Descemet’s membrane increases / decreases in thickness with age
increases
Corneal endothelium: derived from the
neural crest
Pharyngoconjunctival fever is one of the characteristic syndromes, its symptoms last LESS / MORE time than epidemic keratoconjunctivitis
less
The most effective method for preventing nosocomial infection is indeed identification and isolation, but in the previous
14-21 days
Ligneous conjunctivitis - where are the membranes
subtarsal membranes
Trauma with plant material - which fungi
filamentous
Candida keratitis should be suspected in cases of
prolonged use of contact lenses, systemic immunosuppression and diabetes
Adult inclusion conjunctivitis – Treatment
Azithromycin 1 g
Hassall–Henle bodies
Collagen deposits – Descemet’s membrane
Wilson’s disease
Copper deposits – Descemet’s membrane
cystinosis
crystalline deposits are found on the surface of the stroma
epithelial dystrophies
EBMD, Meesmann, Lisch, Gelatinous droplike
epithelial-stromal dystrophies
Reis-Bucklers, Thiel-Benkhe, Lattice, Granular
stromal dystrophies
Macular, Schnyder, Congenital Stromal, Fleck, Posterior amorphous, Pre-Descemet
iridocorneal endothelial syndrome - pathology
metaplasia of epithelioid cells in the endothelium, which can be assessed by specular microscopy
Mooren’s - most common form
unilateral and affects elderly patients with no associated autoimmune disorder
Mooren’s - second form
young people, most commonly Asian/Indian, and is very aggressive, painful and bilateral. An association with HCV has indeed been described
Pellucid marginal degeneration - age compared to keratoconus
later age
Pellucid marginal degeneration - where in cornea
inferior peripheral region
Limbal girdle of Vogt - where in cornea
nasal and temporal limbus (nasal is more common)
Moorn’s and PUK - differential
Mooren’s ulcer is not associated with any systemic autoimmune condition and does not affect the sclera, unlike PUK, which can cause scleritis and usually occurs in individuals with systemic autoimmune diseases
EBOD - % population, M or F
in 6-18% of the population, predominantly women over 50 years of age
EBOD - % suffer from erosions
10% of these patients suffer from recurrent corneal erosion
Ocular cicatricial pemphigoid -sex and age
affects people over 60 years of age, predominantly women (2:1)
Ocular cicatricial pemphigoid - staining
positive immunofluorescence staining of the basement membrane of the conjunctiva, but this test is often negative, even when this diagnosis is strongly suspected
CIN - recurrence
between 33% and 50%
CIN - treatment
Both 5-FU and surgical resection are therapeutic options, as are Mitomycin C and interferon alpha-2beta
Peter’s - pathology
focal loss of Descemet’s membrane and the underlying endothelium
LASIK alters corneal sensitivity and can be the cause of neurotrophic keratopathy - T or F
T
Can atopy cause stem cell deficiency
T
Can pterygium cause stem cell deficiency
T
speed up the resolution of episodes of herpetic epithelial keratitis
oral treatment with Acyclovir 500 mg every 12 hours for 7 days
Hypoaesthesia in herpetic
patchy, but it does depend on the severity, duration and number of episodes suffered
Down - contraindications for which transplants
penetrating keratoplasty and DALK
A patient who had penetrating keratoplasty 18 months ago comes for a post-transplant follow-up visit. Topography shows 7 D of astigmatism at 80 - 260º. Supposing that he has not yet had any sutures removed, which one would you remove first?
At 170º and -10º
anteriorly displaced Schwalbe’s line - what is it
junction of Descemet’s membrane and the trabecular meshwork
