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Miscellaneous > Hypersensitivity > Flashcards

Hypersensitivity Flashcards

1
Q

What is Type I

A

Anaphylactic

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2
Q

What is type II

A

Cell bound

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3
Q

What is type III

A

Immune complex

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4
Q

What is type IV

A

Delayed hypersensitivity

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5
Q

Type I mechanism

A

Antigen reacts with IgE bound to mast cells

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6
Q

Type I examples (2)

A

Anaphylaxis

Atopy (asthma, eczema, hay fever)

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7
Q

Anaphylaxis

A

I

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8
Q

Atopy

A

I

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9
Q

Type II mechanism

A

IgG or IgM binds to antigen on cell surface

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10
Q

Type II examples (7)

A 
Autoimmune haemolytic anaemia
ITP
Goodpastures syndrome 
Pernicious anaemia 
Acute haemolytic transfusion reactions
Rheumatic fever
Pemphigus vulgaris/bullous pemphigoid
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11
Q

Autoimmune haemolytic anaemia

A

II

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12
Q

ITP

A

II

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13
Q

Goodpastures syndrome

A

II

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14
Q

Pernicious anaemia

A

II

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15
Q

Acute haemolytic transfusion reactions

A

II

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16
Q

Rheumatic fever

A

II

17
Q

Pemphigus vulgaris/bullous pemphigoid

A

II

18
Q

Type III mechanism

A

Free antigen and antibody combine

19
Q

Type III examples (4)

A

Serum sickness
SLE
Post streptococcal glomerulonephritis
Extrinsic allergic alveolitis

20
Q

Serum sickness

A

III

21
Q

SLE

A

III

22
Q

Post streptococcal glomerulonephritis

A

III

23
Q

Extrinsic allergic alveolitis

A

III

24
Q

Type IV mechanism

A

T cell mediated

25
Q

Type IV examples (7)

A 
TB
Graft vs host disease 
Allergic contact dermatitis 
Scabies
Extrinsic allergic alveolitis 
MS
Guillian Barre
26
Q

TB

A

IV

27
Q

Graft vs host disease

A

IV

28
Q

Allergic contact dermatitis

A

IV

29
Q

Scabies

A

IV

30
Q

Extrinsic allergic alveolitis

A

IV

31
Q

MS

A

IV

32
Q

Guillian Barre

A

IV

33
Q

Type V mechanism

A

Antibodies that recognise and bind to the cell surface receptors

34
Q

Type V examples (2)

A

Graves’ disease

Myasthenia gravis

35
Q

Graves’ disease

A

V

36
Q

Myasthenia gravis

A

V

Miscellaneous (16 decks)

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