hypersensitivities Flashcards
what is a hypersensitive disease?
immune system reacts in an aberrant manner
what types of hypersensitivity are there?
I
II
III
IV
what is type 1 hypersensitivities?
antibodies against environmental antigens
what is type II hypersensitivity?
antibodeis against cellular antigens
what is type III hypersensitivities?
antibodies in immune complexes
what is type IV hypersensitivities
cellular response to chemicals/antigens
what is type 1 hypersensitivity caused by?
always IgE mediated
inflammation
releases histamine
excessive Th2 environment
what are the symptoms of Type 1 hypersensitivity?
itching
urticaria
increased production of mucous
diseases caused by type I hypersensitivity?
food allergies
allergies to parasites
what do mast cells play in type I hypersensitivity?
release inflammatory molecules
what occurs in rapid degranulation in type I hypersensitivity?
rapid degranulation
extensive sudden acute inflammation
normal inflammation is slow release
what is the insect bite hypersensitivity?
bite causes swelling
type I hypersensitivity in some aniamls
mainly causes nuisance