Hyperparathyroidism Flashcards
what is PTH normally secreted in response to
low ionised calcium
what does PTH do
increases osteoclast activity, releasing calcium and phosphate from bone
increases calcium and decreases phosphate reabsorption in the kidney
what are the causes of hyperparathyroidism
80% solitary adenoma
20% hyperplasia of all glands
<0.5% parathyroid cancer
what are the clinical features of hyperparathyroidism
bones, stones, abdominal groans and psychic moans
what electrolyte abormality do you see in hyperparathyroidism
raised calcium
decreased phosphate
what happens to BP in hyperparathyroidism
increased
what would you see on blood tests in hyperparathyroidism
increased calcium and increased PTH
decreased phosphate
increased ALP from bone resorption
give the two main causes of secondary hyperparathyroidism
decreased vitamin D intake
chronic renal failure
what would you see on blood tests of secondary hyperparathyroidism
decreased calcium
increased PTH
how do you manage hyperparathyroidism
increase fluid intake to prevent stones
excise pituitary adenoma
