Diabetes Insipidus Flashcards

1
Q

what is diabetes insipidus

A

a condition characterised by a deficiency of ADH (cranial DI) or an insensitivity to ADH (nephrogenic DI)

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2
Q

what are the features of DI

A

polyuria
polydipsia
dehydration
symptoms of hypernatraemia

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3
Q

what osmolalities would you see in DI

A

HIGH plasma osmolality

LOW urine osmolality

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4
Q

what is the investigation of choice for DI

A

water deprivation test

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5
Q

how do you manage cranial DI

A
MRI head
test anterior pituitary function 
give DESMOPRESSIN (a synthetic analogue of ADH)
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6
Q

how do you manage nephrogenic DI

A

treat the cause

if it persists try bendroflumethiazide

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