Hypernatraemia Flashcards

1
Q
A
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2
Q

What are causes of hypernatraemia?

A
  • Diabetes insipidus
  • Iatrogenic - excessive saline
  • Osmotic diuresis - e.g. diabetes
  • Primary hyperaldosteronism
  • Drugs - Lithium, tetracyclines, amphotericin B
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3
Q

What are symptoms of hypernatraemia?

A
  • Lethargy
  • Thirst
  • Weakness
  • Iriitability
  • Confusion
  • Coma
  • Seizures
  • Signs of dehydration
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4
Q

What investigations might you consider doing in someone who is hypernatraemic?

A
  • Bloods - U+E’s, Plasma osmolality
  • Urine - Na+ and osmolality
  • Electrolyte-free water excretion
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5
Q

How would you manage hypernatraemia?

A
  • Treat cause - Desmopressin, withdraw nephrotoxic drugs
  • Move to ITU if severe
  • Consider IV 0.9% saline if hypovolaemic
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6
Q

What might a electrolyte free water excretion ratio of > 5.0 indicate in someone with hyperntatraemia?

A

Diabetes insipidus

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