Hyperlipidemias Flashcards

1
Q

Type I: Hyperlipoproteinemia

A
  • rare genetic disorder
  • Lipoprotein Lipase def
  • Apo C-II def
  • elevated chylomicrons
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2
Q

Type IIa: Familial Hypercholesterolemia

A
  • common AD disorder
  • LDL receptor def
  • elevated LDL
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3
Q

Type IIb : Famlial Combined Hyperlipo-proteinamia

A
  • common AD disorder
  • low LDL recptor to Apo B ratio
  • Elevation of VLDL /LDL/TAGs
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4
Q

Type III: Familial Dysbetalipoproteinemia

A
  • rare
  • apo E def
  • elevated IDL (VLDL remnant)
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5
Q

Type IV: Familial Hyperlipemia

A
  • common
  • VLDL overproduction w/ low clearance
  • elevated VLDLs
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6
Q

Type V: Hypertriglyseridemia w/ chylomicronemia

A
  • uncommon
  • VLDL overproduction w/ underproduction Lipoprotein lipase
  • elevated VLDLs w/ chylomicrons
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