Hyperlipidemia Flashcards
Who is screened and when
Men 40yrs and older, women 40yrs old or postmeno
Who would you screen earlier
AAA, DM, CKD, family hx, ED, athloroslorosis, obesity, HIV, COPD, HTN in pregnancy
What are the baseline screening labs
Standard lipid panel LDL, HDL, TG, TC,
GFR & glucose
How do you screen pt with TG level >4.5
Fasting lipids and lipoprotien
When to repeat screening
if FRS <5 = in 5 years, if >5 = annually
What are the guidelines for statin use after 75years
Poor primary prevention but essential secondary prevention
what are the statin indicating conditons
Dm, type 1 >30 years old and longer than 15 years of disease, AAA, athlerosclorosis, CKD
when should statins be used for primary prevention
FRS >10-19%, LDL >3.5, non HDL >4.5, apoB >1.2g/l
Men >50 or women >60 with one of the following:
HTN, impared glucose, big waist circumference, lowe HDL
when should statins be used for primary prevention
FRS >10-19%, LDL >3.5, non HDL >4.5, apoB >1.2g/l, high risk FRS >20%
Men >50 or women >60 with one of the following:
HTN, impared glucose, big waist circumference, lowe HDL
What is clinical athrolslorosi
TIA, stroke, angina, MI, ACS, PAD, carotid disease,
Define AAA
> 3cm
what are the targets
LDL < 2 or 50% reduction, ApoB <0.8g/l, non HDL - <2.6,
if LDL > 5mols - 50% reduction
What other medications can be used?
bile acid sequesterants
Addition of ezetimibe therapy to statins
PCSK9 inhibitors for familiar dyslipidemia or those that statins haven’t been effective
What are the diatary recommendations
Mediterainian diet, plant based oils, nuts, fruits/veggies, olive oil, high fiber, low gylcemic, vegitarian
What are the activity guidelines
150 mins of exercise a week (moderate to vigerous)
