Hypercholesterol

Question 1

Management of Hypercholestrolemia

Answer 1

Lifestyle:
LOW
Exercise
Eat high fibre (fruits and vegetables), choose healthy fats/oils, control portions, limit cholesterol (organ meat and egg yolk), reduce saturated and trans fat (red meat, full fat dairy)
Quit smoking
Limit alcohol
Manage stress

2. Meds
   First line is statins - lower LDL (block enzyme responsible for cholesterol production in the liver)
3. Ezetimibe
   -reduces cholesterol absorption in the GI tract
4. PCSK9 reduce LDL and reduce cardiovascular events.
5. Bile acid sequestration
   -bind to bile acids in the intestine and reduce amount of cholesterol absorbed from food

Question 2

Side effects of statins

Answer 2

Muscle pain, aches or weakness

May increases risk of DM