Hypercalcaemia Of Malignancy Flashcards
What are the features of hypercalcaemia?
‘bones, stones, groans and psychic moans’
What is a feature of hypercalcaemia related to the eyes?
Corneal calcification
What ECG change is associated with hypercalcaemia?
Shortened QT interval on ECG
What cardiovascular condition is associated with hypercalcaemia?
Hypertension
What is the initial management of hypercalcaemia?
Rehydration with normal saline, typically 3-4 litres/day.
What treatment may be used after rehydration for hypercalcaemia?
Bisphosphonates, which typically take 2-3 days to work with maximal effect at 7 days.
What is a quicker alternative to bisphosphonates for hypercalcaemia management?
Calcitonin.
What is another treatment option for hypercalcaemia in sarcoidosis?
Steroids.
When are loop diuretics such as furosemide used in hypercalcaemia?
They are sometimes used in patients who cannot tolerate aggressive fluid rehydration.
What caution should be taken when using loop diuretics in hypercalcaemia?
They may worsen electrolyte derangement and volume depletion.
