Hyperaldosteronism Flashcards
Because of excessive renin stimulating the adrenal glans to produce more aldosterone, serum renin will be high?
This is secondary hyperaldosteronism
What are some causes of primary hyperaldosteronism?
- An adrenal adenoma
- Bilater adrenal hyperplasia
- Familial hyperaldosteronism type 1 and type 2 rare
- Adrenal carcinoma rare
Angiotensin II stimulates the release of what hormone from the adrenal glands
Aldosterone from the adrenal glans
A high aldosterone and low renin indicates the cause is?
Primary Hyperaldosteronism
A high aldosterone and high renin level indicates the cause is?
Secondary hyperaldosteronism
What does Renin do to angiotebsinogen
When the juxtaglomerular cells in the afferent arterioles sense a low blood pressure in the arterioles what hormone do they secrete?
RENIN
When the adrenal glands are directly responsible for producing too much aldosterone. Serum renin will be low as it is suppressed by the high blood pressure.
Pirmary Hyperaldosteronism
What does Angiotensin 1 convert to and where?
Angiotensin II in the lungs with the help of angiotensin converting enzyme
What cells in the afferent arterioles sense the blood pressure in these vessels?
Juxtaglomerular cells
What hormone doe sthe liver secrete in responsie to low blood pressure?
Angiotensin
What does Aldoesterone do?
- Increase Na+ reabsorption from the distal tubule.
- Increase K+ secretion from the distal tubule
- Increase hydrogen secretion from the collecting ducts
What are causes of secondary hyperaldosteronism?
- Renal artery stenosis
- Renal artery obstruction
- heart failure
What type of steroid hormone is aldosterone
Mineralcorticoid
What are aldosterone antagonist?
- Eplerenone
- Spironolactone
