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Hyperadrenocorticism Flashcards

1
Q

80% of CRH comes from

A

Pars distalis of adenohypopsis

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2
Q

20% of CRH comes from

A

Pars intermedia

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3
Q

Posterior Pituitary produces

A

ADH and oxytocin

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4
Q

Anterior pituitary releases

A

ACTH, GH, TSH, FSH, MSH, and prolactin

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5
Q

Anterior pituitary releases

A

ACTH, GH, TSH, FSH, MSH, and prolactin

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6
Q

Stress stimulates hypothalamus to release

A

CRH

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7
Q

CRH stimulates release of

A

ACTH

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8
Q

ACTH stimulates adrenal glands to release

A

Glucocorticoids

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9
Q

What part of the adrenal cortex structure produces steroids

A

Zona fasciculata

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10
Q

Glomerulosa produces

A

Mineralcorticoids

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11
Q

Reticular is produces

A

Sex steroids

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12
Q

Regulation of aldosterone is under influence of

A

Potassium

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13
Q

ACTH stimulates teh adrenal to make

A

Cortisol

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14
Q

Excessive cortisol causes

A

Glucose sparing, increase lypolysis, increase glucofenesis and decrease protein systhesis

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15
Q

Angiotensin 2 stimulates the adrenal gland o make

A

Aldosterone

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16
Q

ACTH stimulates teh adrenal to maek

A

cortisol

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17
Q

target organ of aldosterone is

A

kidney

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18
Q

aldosterone affect on Na

A

increases absorption

19
Q

aldosterone affect on K

A

increases excretion of K

20
Q

aldosterone affect on H

A

increases excretion H

21
Q

3 types of hyperadrenocorticism

A

Pituitary depend, Adrenal dependet, and iatrogenic

22
Q

what sex is more likely to have cushings in dogs

23
Q

median age of dogs with cushings

A

9 - 11 years

24
Q

cats with cushings usually also have

25
Q

Signalment for Pituiary dependent cushings

A

smaller toy breeds

26
Q

signalment for ADH

A

50 - 50 small to large

27
Q

common clinical signs of cushings

A

PU/PD, polyphagia, panting and pot belly

28
Q

with cushings what significant CBC do we find

A

stress leukogram

29
Q

what do ultrasound look like in PDH

A

normal to large adrenals

30
Q

what do ultrasound look like in ADH

A

1 big and 1 small, vascular invasion, retroperitoneal hemmorhage

31
Q

what is most common form of hyperadrenocorticism

A

pituitary dependent

32
Q

PDH casues what acth

33
Q

ADH causes what Acth

34
Q

which is independet of ACTH

35
Q

adrenal rumor will

A

produce excess cortisol

36
Q

pituitary tumor will

A

increase ACTH and cortisol

37
Q

adrenal tumor will end up leacing to

A

decreased ACTH

38
Q

most cats have what type of cushings

39
Q

key presenting signs for cats with PDH

A

Diabetes mellitus, alopecia, thin fragile skin

40
Q

what fraction of cats with HAC have skin fragility

41
Q

weight loss in cats is when

A

unregulated DM and concurrectHAC

42
Q

weight gain in cats is when

A

unregulated DM and acromegaly

Endocrine (7 decks)

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