Hydroxyzine

Question 1

What are the two different formulations of Hydroxyzine

Two types

Answer 1

Pamoate (Vistaril)

Hydrochloride (Atarax)

Biggest difference is Atarax can come in 10 mg

Question 2

Classification

Answer 2

Antihistamine (1st Gen)
Anticholinergic with CNS effects

CNS Effects = “Mad as a hatter”

Anticholinergic : Constipation, confusion, dry mouth, urinary retention

Question 3

Indicators

Answer 3

Anxiety

Itchy skin

Insomnia

Question 4

Off-label

Answer 4

Headaches

Question 5

Can cause this disorder

Long term risk for increased usage

Answer 5

Dementia

Question 6

Dosing for anxiety

Answer 6

25 - 50 mg/ q4-6 hours

Question 7

Dosing for insomnia

Answer 7

50 - 100 mg/HS

Should take before bedtime

Question 8

How should you think of Hydroxyzine in comparison to Diphenhydramine

Answer 8

A less sedating Benadryl

Question 9

Goal of hydroxyzine

Answer 9

Take the edge off

Not completely get rid of anxiety.

Question 10

Population to avoid

Answer 10

Elderly

pregnancy

Question 11

Renal Impairment

Answer 11

Nothing

Question 12

Liver Impairment

Answer 12

Nothing

Question 13

Cardiac Impairment

Answer 13

Nothing

Question 14

Elderly

Answer 14

Avoid with those who have dementia

Question 15

Habit forming

Answer 15

No

Question 16

Taper

Answer 16

No

Question 17

How does it work

Answer 17

Blocks Histamine 1 receptors

Causes sedations