Gabapentin Flashcards

1
Q

Another name for Gabapentin

A

Neurontin

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2
Q

Class of drug for Gabapentin

A

Antiepileptic

Prevents seizures

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3
Q

Main indicators for Gabapentin

A

Seizures

Restless leg syndrome

Neuralgia (Nerve Pain)

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4
Q

Off label indicator

A

Anxiety

Alcoholism Withdrawal

“Good for MH patients with neuropathy.”

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5
Q

How does Gabapentin work:

A

It blocks voltage gated calcium channels

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6
Q

Main side effects

A

SEDATION

dizziness

Ataxia - involuntary coordination

fatigue

Ask about bilateral EDEMA

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7
Q

What organ to monitor with the use of Gabapentin

A

Kidney

You can still give even with Abnormal Kidney function

You may have to increase dosage after Hemodialysis

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8
Q

Minimal effective dosage for Gabapentin

A

300 mg/TID

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9
Q

Dosage for Seizures

A

300 mg/TID

You can start initially

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10
Q

How to titrate generally

A

Day 1: 300 mg/ QD
Day 2: 300 mg/BID
Day 3: 300 mg/TID

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11
Q

Dosage for insomnia or nightmares

A

300 - 600 mg/ HS

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12
Q

Usual maximum dosage

A

300 mg/ TID

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13
Q

Biggest risk factor (s) of Gabapentin usage

A

Diversion

Abuse

Respiratory Distress

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14
Q

Taper?

A

Yes

Over one week

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15
Q

Habit forming

A

No

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16
Q

Risk of sudden D/C

A

Seizure threshold lower

Withdrawal effects

Withdrawal: Disorientation, anxiety, palpitation, sweating and abdominal cramps

17
Q

Kidney Impairment

A

Lower dosage (See Stahl)

Add another dosage after dialysis is done

18
Q

Liver Impairment

A

Nothing

This is a good thing. There are no interactions concerns.

19
Q

Cardiac Impairment

A

None

20
Q

Elderly population

A

You may need to lower dosage

Beware: Peripheral edema or ataxia