Hydrops Flashcards
Fetal Hydrops
an abnormal accumulation of serous fluid in at least two body cavities or tissues
Non-Immune Hydrops
defined by the absence of a detectable circulation antibody against RBCs in the mother. today 90% were non-immune due to availability of Rhesus (RH) anti D immunoglobulin.
Immune Hydrops
occurs when a sensitized mother develops antibodies to fetal RBCs. in the 1970s 80% of cases were immune in origin.
Hydrops US Findings
Fetal Ascites
Fetal Pleural Effusion
Pericardial Effusion (cardiomegaly)
Subcutaneous Edema
Placentomegaly
Placental edema is a late sign in hydrops. US: thickened, echogenic, spongy, or ground glass. thickness more than 5 cm in 3rd TM.
Rhogam
Removes RH positive fetal cells from the mother’s bloodstream before her body recognizes them and begins making antibodies. all mothers who are RH negative receive a shot of Rhogam around 28 weeks.
Anasarca
generalized edema with accumulation of serum in subcutaneous connective tissue. goes with Nonimmune hydrops.
Nonimmune Causes : Cardiovascular
Obstructive lesions (left or right heart hypoplasia, single ventricle). Tumors (teratoma, rhabdomyoma)
Nonimmune Causes: Neck/Thorax
Cystic hygroma
cylothorax/hydrothorax
Nonimmune Causes: Gastrointestinal
Hepatic (cirrhosis, hepatitis, tumor, polycystic disease)
Bowel (duodenal, jejunal atresia)
Nonimmunes Causes: Urinary Tract
Polycystic
Prune Belly Syndrome
Nonimmunes Causes: Infections
cytomegalovirus
Nonimmune Causes: Maternal
Severe Diabetes Mellitus
Severe Anemia
Severe hypoprotenemia
Indoemethacin use (premature closure of ductus anteriosus)
Nonimmune Causes: Placental
Chorioangioma
Placental and umbilical vein thrombosis
Diabetes
Increased risk for unexplained still-births. fetus increases production of insulin substantially in order to use this extra sugar. Fetus is overfed while in the uterus