Hydralazine, Diuretics, CCB Flashcards
Hydralazine long term use can cause what disease process
systemic lupus syndrome
how does hydralazine lower the blood pressure
direct systemic arterial vasodilator
why should we not give hydralazine to patients with MI or coronary disease
the arterial vasodilation produces a reflex sympathetic response increase HR and contractility.
hydralazine is effect at reducing after load -what type of disease process is this benefit used for
heart failure.
in the treatment of essential HTN, what medications are considered first line
diuretics continue to be first line oral agents used for essential HTN
what diuretics are initially prescribed
thiazide drugs
when do we start prescribing loop diuretics
when thiazide drugs stop working
what do thiazide and loop diuretics cause
potassium and magnesium loss requiring replacement.
what drug is considered successful in treating HTN in the elderly, African Americans, and salt sensitive patients
CCB
what do PDE inhibit the break down of
cAMP and cGMP
what is the effect of PDE inhibitors
increased inotropic effects and vasodilation
nitric oxide functions
chemical messenger platelet regulation neurotransmitter in the CNS immune regulation gastrointestinal smooth muscle relaxation
nitric oxide inhalation effects
relaxation of the pulmonary smooth muscle
