Hunger and chemical senses Flashcards
What does sweetness signify?
Energy-rich and vitamin-rich foods.
What does saltiness signify?
The presence of electrolytes.
What does umami signify?
The presence of glutamate (an amino acid).
What do bitterness and sourness signify?
Potentially harmful, spoiled, or poisonous foods.
How does junk food affect the brain?
It can change the brain over time, especially with continuous intake.
What was the effect of the Dutch famine on babies in gestation?
Increased obesity, diabetes, and cardiovascular disease.
How did the rise of agriculture affect human survival?
It stabilized food availability and reduced feast-or-famine risks.
Do all senses contribute to taste?
Yes, all senses play a role in taste.
What regulates hunger and satiation?
Blood glucose levels.
What is the brain’s primary energy source?
Glucose
How is glucose stored and released?
Stored as glycogen in the liver and released when blood glucose is low.
Describe the negative feedback loop of glucose.
↑ blood sugar → insulin → glucose uptake + glycogen/adipose storage
↓ blood sugar → glycogen converted back into glucose
Depleted glycogen = hunger signal
What hormone promotes food-seeking behavior?
Neuropeptide Y (NPY)
What happens when blood sugar increases?
The pancreas secretes insulin, prompting cells to absorb and store glucose.
What happens as blood sugar decreases over time?
The liver converts glycogen to glucose and releases it into the blood.
What triggers hunger?
Low glucose and glycogen levels; increase in Neuropeptide Y (NPY).
What sends satiety signals to the brain?
Stomach stretch receptors (via the vagus nerve)
Gastrointestinal digestive hormones
Liver monitoring glucose
What is CCK
Cholecystokinin
Short-term satiety hormone
What does CCK do?
Signals the brain to stop eating.
Where is CCK produced?
In the small intestine.
How is fat stored?
As adipose tissue.
Why is fat ideal for long-term energy storage?
1g of fat = 9 kcal vs. 1g of glycogen = 4 kcal.
What is leptin?
A hormone secreted by fat cells that signals low energy storage levels.
What does leptin do in the brain?
It inhibits NPY in the hypothalamus, therefor reducing appetite.