-Humidity and aerosol therapy Flashcards

1
Q

-Humidity and aerosol therapy

A

-Humidity therapy is the addition of water to the gas delivered to the airways

-Goals of humidity therapy is to provide adequate heat and humidity, treat hypoxia, prevent airway response to cold air, and aid in removal of thick secretions

-Otherwise known as invisible water/moisture it is molecular and you cannot see it

-Can be cool or heated
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2
Q

-Humidity

A

-Most medical gasses are 100% dry

-Supplying enough water vapor to make it comfortable for the patient

-Heating the gas provide 100% relative humidity at body temperature

	-Especially when the upper airway is bypasses must heat and humidify to reach 100% body humidity
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3
Q

-Humidifiers Bubblers

A

-1. Bubbler > 4 lpm flow on NC can be used at lower flow if pt experiencing discomfort

	-One of the most common used for low flow

	-Gas conducted below the surface of water and allowed to bubble back to top

	-Have a diffuser, device to break the gas into smaller bubbles

	-Pop off valve set at 2 PSIG or 40 mmHg

	-Not effective for flows greater than 6LPM ( choose another device)
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4
Q

-Humidifiers -2. Pass-over or blow by humidifiers

A

-2. Pass-over or blow by humidifiers

	-Direct gas over the surface of a body of water

	-Efficiency- rather than flow

	-Use maybe some home CPAP. BIpap units
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5
Q

-Humidifiers -3. Cascade

A

-Advanced type of bubble humidifier

	-Was commonly used with ventilators or other high flow conditions

	-Heating element is submerged into water

	-Heating control with reference should be used near patients

	-Monitoring thermometer should be used near patient

	-Can be used without heat but only provided 100% body humidity if heated
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6
Q

-Humidifiers -4. Wick Humidifiers

A

-Used with vents and hood, has temp control you set

	-Made of substance such as sponge or paper

	-Absorbs water by capillary action from concha container

	-Gas passes through or next to wick to take on humidity
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7
Q

-Humidifiers -5. Heat moisture exchanges (HME)

A

-Short term use (with artificial airway only)

	-Place between artificial airway and wye of vent circuit

	-Exhaled gasses at body humidity enter HME, material absorbs heat and moisture back into PT with next breath

	-During inhalation, gas passing through the exchanger is warmed and humidified before being delivered to the trachea. Think of this as a artificial nose

	-Must be removed during aerosol therapy (neb Treatment)

	-If Pt is not normal temp can not use
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8
Q

-Humidifiers -6. Heated Humidifers/ Heated Wire circuits

A

-Fisher and Paykel most commonly used with vent

	-Heat increases capacity of gas to hold water vapor

	-If the upper airway is bypassed, 100% relative humidity is necessary to humidify inspired gasses

	-May be necessary to heat above body temperature since gas will coll as it passes through tubing to the patient. Has set temp and actual monitored temp

    	-As gas cool, condensation occurs

		-Must be angled down and away from the patient

		-Must be drained to avoid water accumulation
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9
Q

-Problem Solving-Bubbler

A

-Safety pop-off valve

		-Set to 2 PSIG

		-For crimping/ blockage of tubing -will whistle as indication

	-Contamination- do not attempt to refill prefilled bubblers
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10
Q

-Problem Solving -Condensation

A

-Condensation

	-Can disrupt and occlude air flow

	-Cause aspiration if it enters the patient's airway

		-Position circuit to drain condensate away from patient

	-Infection risk

		-Colonized within hours of bacteria

		-Treat as infectious waste (goggles/ Gloves)
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11
Q

-Measuring Humidity -Partial Pressure

A

-Because it is a gaseous vapor- excerpts pressure

	-Vapor pressure, maximal pressure that water can excerpt at a given temp

	-As humidity or temp increases, pressure increases

		-As temp increases, velocity of particles increase
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12
Q

-Measuring Humidity -Absolute Humidity

A

-Absolute Humidity

	-Actual water content of a gas

	-Determined by extracting water vapor from know volume of gas and weighing water

	-The common unit of measuring is mg/L

	-Maximum absolute= 44 mg/L (weight) or 47 mmHg (water vapor pressure in lungs)
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13
Q

Normal body humidity at normal body temp

A

Normal body humidity at normal body temp= 43.8mg/L (44) or 47.1 mmHg (47) vapor pressure

-Body humidity at normal body temp 37 deg celsius is at maximum absolute (capacity 43.8mg/L (44) meaning it is fully saturated: holding all the water it can.

-Body Humidity- the relative humidity at body temperature expressed as a percent (what we ARe providing the patient)

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14
Q

-Measuring Humidity -Calculation

A

-Calculation

	-1. If we know temp of gas and absolute humidity of gas or pressure of gas

	-2. Can calculate the % of relative humidity

-RH= Content (absolute humidity) / Capacity * 100

		-Content will always be given to you

-Example

	-The amount of moisture in a given volume of a gas at 31C contains 24mg/L of gas. Calculate the relative humidity. At 31C, the air can hold 32.01mg/L

	-RH= Content/ Capacity *100

		-So 24mg/32.01*100

			-=.748*100=74.9 or 75%
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15
Q

-Inspissated secretions ,

A

secretions thickened because of dehydration

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16
Q

Measuring Humidity -Relative humidity

A

-Relative humidity

-Percentage expression of the actual water vapor content as compared to the capacity of the gas to carry water at any given temperature

-Capacity increases as temp of the gas rises

	-As temp of water increases, velocity of molecules increases
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17
Q

-Humidity deficit

A

-Humidity deficit is the amount of water vapor the body must add to the inspired gas to achieve saturation at body temperature (what we are NOT providing)

-Humidity deficit = Ideal- actual

	-In other words, capacity-content=Deficit

	-(Ideal) capacity is 43.8 or 44mg/L

	-Content must be given to you!!

	-Answer may be converted to % see examples
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18
Q

-Bland Aerosol Therapy

A

-Liquid particles suspended in a gas, you can see it

   -Sterile water, hypotonic, isotonic, or hypertonic saline all used for bland aerosol:

	-Upper airway edema

	-Laryngotracheobronchitis (LTB) or croup

	-Subglottic edema

	-Post-op management of upper airway

	-Bypassed upper airway

	-Sputum induction or mobilization of secretion
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19
Q

-Equipment

-1. Large volume jet nebulizer (aerosol generators, air entrainment nebulizers)

A

-Most common

	-Pneumatically powered (gas powered)

	-Baffled to keep large particles from going to patient

	-Can be heated to increase amount of aerosol

	-FiO2, adjusted via air entrainment port

	-Higher FiO2 (> equal to 60)

	-May need to “Tandem” together two devices if not meeting demand or total flow need

	-Only time you would heat is if pts upper airway is bypassed
20
Q

-Equipment
-Interface devices to deliver aerosols (of Large volume jet nebulizer)

A

-Aerosol mask

	-Face tent

	-Trach Mask- used with trached patients

	-T-Piece/ Briggs adapter, intubated or trached patient

	-Enclosures, oxygen mist tents and hoods

	-Problems, CO22 build up and heat retention
21
Q

-Bland Aerosol Therapy in general uses

A

-Can be used for sputum induction (USN)

	-Short term therapy

	-Hypertonic saline (3-10%) aerosol

	-Mobilizes secretions and causes cough get sputum, not saliva

-Can be used to gap humidity deficit in PTs with artificial airways when heated

-Treat edema when cool
22
Q

-Bland Aerosol Therapy in general-Troubleshooting

A

-Most common problems

		-Infection, low mist production, overhydration, bronchospasm, noisy

	-Infection, do not refill water bottles of LVJN, change put equipment per protocol, clean chambers of USN
23
Q

-Bland Aerosol Therapy in general-Low mist production

A

-Check for obstruction of jet, check fluid levels in USN/LVJN

	-Ensure DISS connection and flowmeter setting is correct may need to increase flow

	-Ensure water has not accumulated in corrugated tubing of LVJN will increase Fi02 same as ports on venti being blocked
24
Q

-Bland Aerosol Therapy in general-Bronchospasm

A

-Every bland aerosol can cause bronchospasms

	-Initially assess and reassess patient periodically

	-If occurs stop treatment, provide 02, start bronchodilator
25
Q

-Bland Aerosol Therapy in general-Particle size

A

-> equal to 10 Um impact in nasal passage

	-5-10 um impact in oro-hypopharynx

	-2-5 um deposit in lower airways
26
Q

-Aerosol Drug Administration

A

-Dosing of aerosolized medication is imprecise

-Humidity influences the delivery of aerosol medication

-Drug formulation dictates which aerosol options are available for delivery of a specific medication
27
Q

-Aerosol medication delivery devices

A

-Jet nebulizer (small volume neb SVN, large volume neb or continuous neb)

	-Mesh nebulizer (aerogen)

	-Soft mist inhaler (SMI)

	-Portable ultrasonic nebulizer (USN)

	-Pressurized metered dose inhaler (pMDI)

	-Metered dose inhaler with spacer or holding chambers

	-Dry powder inhaler

-For any inhaled medication-pt or neb chamber needs to be in upright position
28
Q

-Small Volume medication nebulizers (SVN)

A

-Pneumatically powered

	-Design

		-Medication reservoir 		

		-Baffle

		-Gas inlet jet

		-Output port

	-Also available breath actuated/ breath enhanced
29
Q

-Large volume medication Nebulizer (LVN)

A

-Used to deliver medication over long periods of time such as several hour albuterol (continuous neb)

	-Brand names= Heart/ Westmed, hope
30
Q

-Equipment Medication administration

-Low flow medication nebulizers

A

-Powered by flow of 2-3lpm

-Can run in line with vent circuitry without greatly increasing volumes delivered to patient (NICU) also utilized for 30 min to 1 hour long nebs in ER
31
Q

-Equipment Medication administration

-SPAG- small particle aerosol generator

A

-Used to deliver Ribavirin (Virazole) for RSV

-Uses drying chamber to achieve uniform particle size

-Hooked gas source such as blender has 2 flowmeters we set (6-8LPM) and PSI to 26-32
32
Q

-Aerosol Drug Administration

-Mesh Nebulizer

A

-Use electricity to vibrate a piezo element that moves liquid formulations through a fine mesh to generate aerosol

	-The diameter of the mesh or aperture determines the size of the particles generated

	-Mesh nebulizers are very efficient and result in minimal residual volume
33
Q

-Aerosol Drug Administration

-Two types of mesh Nebs

A

-Activate Vibrating mesh , have an aperture plate with 1000-4000 funnel shaped holes vibrated by a piezo ceramic element that surrounds the plate

	-Passive mesh utilizes an ultrasonic horn to push fluid through a mesh
34
Q

-Aerosol Drug Administration

Most common used

A

Aerogen

35
Q

-Aerosol Drug Administration

-Soft mist inhaler (Respimat)

A

-Propellant, free soft mist inhaler

	-Utilizes mechanical energy in the form of a tensioned spring to generate the soft aerosol plume

	-Energy from turing the transparent base to the right one-half turn draws a predetermined metered volume of solution from medication cartridge to be delivered
36
Q

-Aerosol Drug Administration
-Ultrasonic neb (small volume)

A

-Available for aerosol drug delivery (Not suspension such as Budesonide)

	-May or may not use water filled couplant compartment, with medication placed in a cup directly over the transducer

	-Advantage, battery powered, so provided convenience
37
Q

-Aerosol Drug Administration

-Pressurized metered dose inhaler (pMDI)

A

-Most commonly prescribed method of aerosol delivery

	-Used to administer bronchodilators and anti inflammatory agents

	-Typically single patient use

	-Has a specific quantity of medication

	-Requires slow inspiratory flow (<30l/min) with a breath hold needed in sync with a patient able to follow directions. If contains a steroid must rinse mouth
38
Q

-Aerosol Drug Administration

-Spacer

A

-Spacer, a simple open ended tube or holding chamber that provides space for the pMDI plume to expand and incorporates a one-way valve that permits the aerosol to be drawn from the chamber during inhalation only

		-Great for children or uncoordinated PTs to act as a holding chamber for medicine due to the one way valve
39
Q

-Aerosol Drug Administration

-Dry powdered inhalers (DPI)

A

-DPIs, create aerosols by drawing air through a dose of powdered medication

	-Flow driven, requires fast deep inhalations

	-Do not contain propellants

	-Breath-actuated so dependent on patient

	-Single dose and multiple dose devices

	-Ether dispenses a set amount of powder or uses a system that pierces a capsule of powder to be inhaled
40
Q

-Hazards of medication/ Nebulizer therapy

A

-Medication, adverse action terminate TX if adverse reaction occurs
120 heart rate wait and switch to xopenex

   -Infection, usually gram negative bacilli (Pseudomonas, Legionella pneumophila) from equip not cleaned or changed out appropriately

	-Airway reactivity

	-Drug concentration changes during nebulization
41
Q

Ultrasonic Nebulizers

	-Electrically powered
A

-Piezoelectric Crystal

		-Generates aerosol

		-Converts radio waves into mechanical vibration

		-Vibration through couplant or directly to solution chamber

	-Gas enters solution chamber, pick up aerosol, exits
42
Q

Ultrasonic Nebulizers

-Frequency

A

-Preset You Cannot Change!!!

		-Determines size of particles

		-MMAD mass mean aerosol diameter

			-1.24-2.25 MHz=2.5-6 UMs (microns)
43
Q

Ultrasonic Nebulizers

-Amplitude of signal (aka:output)

A

-Adjustable

		-Determines amount of aerosol produced

	-Source and flow of gas determines density (mg/L) and total output (ml/min)

	- Increase flow/ fan= Decrease Density   decrease flow/ fans= Increased density
44
Q

Ultrasonic Nebulizers

Benefits

A

-Recommended for sputum induction/ thick tenacious

-Has the largest total fluid output of any device

45
Q

Ultrasonic Nebulizers

-Problems

A

-Can increase airway reactivity/ bronchospasm due to massive rehydration of secretions

-Contamination due to increased particle size and reservoir