Humanistic outcomes

Question 1

What is the ECHO model?

Answer 1

Economic
Clinical
HUmanistic

Question 2

What falls under humanistic?

Answer 2

utility
functional status
willingness to pay
patient satisfaction

Question 3

What is under the title of functional status?

Answer 3

physical
mental
social
energy
level of pain

Question 4

What is the short form 36?

Answer 4

total score of 100
35 questions about health, functioning
+ one question about how it has changed over the past year

Question 5

What is an issue with short form 36?

Answer 5

takes alot of time to do

Question 6

What other method can be done instead of short form 36?

Answer 6

SF-12

Question 7

What is an issue with functional outcome measures (generic and disease specific)

Answer 7

no sensitivity to measure effect of an intervention

Question 8

What is willingness to pay? What is indirect and Direct?

Answer 8

• monetary value for outcome
  indirect= inferred from observing
  Direct= open by asking how much they would pay, close asking yes or no to a bunch of prices

Question 9

How is willingness to pay measured through closed questions?

Answer 9

Gives you a senario
EX.Choice 1= SOME relief in 2 days, no s/e, 15$
Choice 2= SOME relief in 4 days, s/e, 5$

Question 10

DO people rather have more relief and side effects or some relief with no side effects?

Answer 10

PREFER NO SIDE EFFECTS

Question 11

How can we measure patient satisfaction?

Answer 11

Ask how was their service
PREM’s= questionaires

Question 12

Is hydroxyzine a good option for GAD?

Answer 12

Stat sig over placebo don’t know compared to other treatments (not powered) Very little improvement though
add on territory

Question 13

Is treatment with prn symbicort good in mild asthma?

Answer 13

compared to placebo+ SABA and BID bud
Valid
much better as NNT is super low

Question 14

Do you pick a LAMA or LABA for initial treatment for mild COPD?

Answer 14

No stat sig difference in ability
BUT if at least 1 exacerbation then stat sig when using LAMA

Question 15

Is varenicline more effective that NRT?

Answer 15

was stat significant NOT for women after 6 months
Better in the 55 and older group

Question 16

Are Levonorgestrel IUDs effective for emergency contraception

Answer 16

NO POWER CALC, unblinding occured
NOT stat sig compared to copper crossed one
stat sig for continutation pregnancy reduction

Question 17

Do BC raise VTE?

Answer 17

observational so cant prove
seems to be an association- especially newer ones
MA- found that there is though

Question 18

How does implant compare to other long acting BC?

Answer 18

Higher discontinuation rate due ro bleeding

Question 19

Is gentamicin a good alternative to ceftriaxone for gonorrhea?

Answer 19

NOT a good alternative

Question 20

What is the impact of vortioxetine on MDD?

Answer 20

NOT Stat significance of lower depression score
secondary is significant

Question 21

What role does atypical antipsychotics have in MDD?

Answer 21

NO confidence intervals
NO stat significance
no role

Question 22

What is role of ketamine in MDD?

Answer 22

stat sig over midazolam

Question 23

What impact does lemborexant have in insomnia?

Answer 23

stat significance-lowers SL

Question 24

Does ASA lower risk of VTE after hip surgery?

Answer 24

Not stat significance

Question 25

Do MRA’s lower death +hospitalization for HF-rEF?

Answer 25

Cohort study- so only an association

Question 26

Do SGLT2i lower death and hospitalization in HF-rEF?

Answer 26

yes stat sig

Question 27

What are the elements fo a critical appraisal?

Answer 27

PICO
Confounding- similar,ITT,random
bias-blinding
chance- power calc
Valid?
Results-Best Worst case
Generalizable?
Math