Humanistic outcomes Flashcards
What is the ECHO model?
Economic
Clinical
HUmanistic
What falls under humanistic?
utility
functional status
willingness to pay
patient satisfaction
What is under the title of functional status?
physical
mental
social
energy
level of pain
What is the short form 36?
total score of 100
35 questions about health, functioning
+ one question about how it has changed over the past year
What is an issue with short form 36?
takes alot of time to do
What other method can be done instead of short form 36?
SF-12
What is an issue with functional outcome measures (generic and disease specific)
no sensitivity to measure effect of an intervention
What is willingness to pay? What is indirect and Direct?
- monetary value for outcome
indirect= inferred from observing
Direct= open by asking how much they would pay, close asking yes or no to a bunch of prices
How is willingness to pay measured through closed questions?
Gives you a senario
EX.Choice 1= SOME relief in 2 days, no s/e, 15$
Choice 2= SOME relief in 4 days, s/e, 5$
DO people rather have more relief and side effects or some relief with no side effects?
PREFER NO SIDE EFFECTS
How can we measure patient satisfaction?
Ask how was their service
PREM’s= questionaires
Is hydroxyzine a good option for GAD?
Stat sig over placebo don’t know compared to other treatments (not powered) Very little improvement though
add on territory
Is treatment with prn symbicort good in mild asthma?
compared to placebo+ SABA and BID bud
Valid
much better as NNT is super low
Do you pick a LAMA or LABA for initial treatment for mild COPD?
No stat sig difference in ability
BUT if at least 1 exacerbation then stat sig when using LAMA
Is varenicline more effective that NRT?
was stat significant NOT for women after 6 months
Better in the 55 and older group
Are Levonorgestrel IUDs effective for emergency contraception
NO POWER CALC, unblinding occured
NOT stat sig compared to copper crossed one
stat sig for continutation pregnancy reduction
Do BC raise VTE?
observational so cant prove
seems to be an association- especially newer ones
MA- found that there is though
How does implant compare to other long acting BC?
Higher discontinuation rate due ro bleeding
Is gentamicin a good alternative to ceftriaxone for gonorrhea?
NOT a good alternative
What is the impact of vortioxetine on MDD?
NOT Stat significance of lower depression score
secondary is significant
What role does atypical antipsychotics have in MDD?
NO confidence intervals
NO stat significance
no role
What is role of ketamine in MDD?
stat sig over midazolam
What impact does lemborexant have in insomnia?
stat significance-lowers SL
Does ASA lower risk of VTE after hip surgery?
Not stat significance
Do MRA’s lower death +hospitalization for HF-rEF?
Cohort study- so only an association
Do SGLT2i lower death and hospitalization in HF-rEF?
yes stat sig
What are the elements fo a critical appraisal?
PICO
Confounding- similar,ITT,random
bias-blinding
chance- power calc
Valid?
Results-Best Worst case
Generalizable?
Math
