Human Population Evolution and Migration Flashcards

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1
Q

T/F. Mitochondrial DNA (mtDNA) is particularly useful in analysing the recent evolution & subsequent migration of human populations as it is non – recombining & is directly inherited through the maternal line. Non - recombining Y chromosome sequences, w/c are inherited through the paternal lineage, have been similarly used.

A

True.

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2
Q

____ shows the deduced ancestral relationships between different populations. When such data are combined w/ the calculated ____ for the studied sequences, the timing of early events within human pre - history can be estimated. In addition, by taking into account the known geographical distribution of the lineages or populations within the phylogenetic tree or network, generating the so-called ____, the past movements of humans between regions can be estimated

A

Phylogenetic tree; mutation rates; phylogeography

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3
Q

A large privately funded study, the ____, is currently underway to investigate these population movements from DNA evidence in much greater detail using DNA samples that are being collected from up to 100,000 indigenous people throughout the world.

A

Genographic Project

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4
Q

Studies of____ from modern human samples from native populations have provided support for the ____ model of human evolution.

A

mtDNA; Recent African Origin

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5
Q

This model involves the evolution of Homo sapiens from Homo erectus in several different regions of the world, independently. Has now been become less popular.

A

Multiregional model

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5
Q

This refers to the hypothesized relatively recent colonization of the world by modern humans who evolved from Homo erectus in sub - Saharan Africa and then, beginning between 50 and 60 thousand years ago, migrated through the rest of the world.

A

African Origin model of human evolution

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6
Q

T/F. The result of migration is that genetic diversity is now much greater in distantly migrated populations such as Native Americans than in native Africans.

A

False. At each stage of the migration only a subgroup broke away from the established population, taking w/ it only a fraction of the existing genetic diversity. Hence Africans are more genetically diverse than distantly migrated populations.

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6
Q

T/F. The Out - of - Africa model has also now been supported by analysis of Y chromosome markers, by recent whole - genome SNP analyses and even by DNA analyses of microorganisms such as Helicobacter pylori bacteria carried by migrating humans.

A

True.

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7
Q

Working backwards through evolution to a common ancestor can be achieved by a technique known as ____.

A

coalescence analysis

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7
Q

The most recent common ancestor (MRCA) for the mtDNA of all the sampled individuals, the _____, has been estimated to have lived around 171,000 years ago in East Africa. Similarly, the MRCA of the Y chromosome sequences, the _____, can be determined.

A

mitochondrial Eve; Y chromosome Adam

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8
Q

T/F. In general, calculated MRCAs differ according to w/c genomic loci are undergoing coalescence analysis.

A

True.

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9
Q
A
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