human microbiome Flashcards

1
Q

What is the human microbiome?

A

The set of microorganisms that inhabit the human body.

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2
Q

True or False: The human microbiome only consists of bacteria.

A

False. The human microbiome includes bacteria, viruses, fungi, and other microbes.

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3
Q

What is the main function of the human microbiome?

A

To help with digestion, protect against pathogens, and regulate the immune system.

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4
Q

Where is the human microbiome primarily located?

A

In the gut, skin, mouth, and other mucosal surfaces.

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5
Q

What is dysbiosis?

A

An imbalance in the microbial community of the human microbiome.

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6
Q

What factors can influence the composition of the human microbiome?

A

Diet, antibiotics, age, genetics, and environment.

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7
Q

What is the role of probiotics in the human microbiome?

A

To introduce beneficial bacteria to the gut to improve microbial balance.

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8
Q

What are some diseases that have been linked to disruptions in the human microbiome?

A

Obesity, inflammatory bowel disease, and allergies.

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9
Q

How does the human microbiome contribute to the immune system?

A

By training immune cells and providing a barrier against harmful pathogens.

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10
Q

What is the term for the collection of genes in the human microbiome?

A

The microbiome gene pool.

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11
Q

Fill in the blank: The human microbiome is estimated to contain around ___________ microbial cells.

A

100 trillion

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12
Q

What is the main difference between the gut microbiome of infants and adults?

A

Infants have a less diverse gut microbiome compared to adults.

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13
Q

True or False: The human microbiome is static and does not change over time.

A

False. The human microbiome can change in response to various factors.

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14
Q

What is the role of prebiotics in the human microbiome?

A

To provide nutrients for beneficial bacteria in the gut.

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15
Q

How can antibiotics impact the human microbiome?

A

By reducing the diversity of microbial species and potentially leading to dysbiosis.

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16
Q

What is the term for the study of the human microbiome and its interactions with the host?

A

Microbiome research.

17
Q

What are some common methods used to analyze the human microbiome?

A

DNA sequencing, metagenomics, and microbial culturing.

18
Q

True or False: The human microbiome is only found in the gut.

A

False. The human microbiome is found in various parts of the body.

19
Q

What is the potential impact of the human microbiome on personalized medicine?

A

It could help tailor treatments based on an individual’s unique microbiome composition.

20
Q

What can disrupt the human microbiome and lead to dysbiosis?

A

Antibiotics, poor diet, stress, and certain diseases.

21
Q

What is the significance of the gut-brain axis in relation to the human microbiome?

A

It highlights the bidirectional communication between the gut and the brain through the microbiome.

22
Q

How does the human microbiome contribute to nutrient absorption?

A

By breaking down complex carbohydrates and producing certain vitamins.

23
Q

What is the role of the skin microbiome?

A

To protect against pathogens and maintain skin health.

24
Q

What is the term for the specific community of microbes that inhabit a particular body site?

A

Microbiota.

25
Q

Factors affecting microbiota

A

Host genetics, diet, age, mode of birth, antibiotics, exercise, smoking, geographical location

26
Q

Development of the microbiota

A

In uterus, childbirth, breastfeeding, childhood,adults

27
Q

What is metagenome

A

complex formed by the genetic material of the microbiome and the host

28
Q

What are metagenomics

A

analysis of the genetic material of the bacteria, directly from a sample of the medium under study

29
Q

Define microbiome

A

Full collection of genes of all the microbes of the human body

30
Q

What are the two major microbial phyla

A

Firmicutes like bacillus, listeria, staphylococcus, enterococcus, lactobacillus and streptococcus, and Bacteriodetes like flavobacteria and porphyromonaa