Human Alimentary Canal: Structure & Function, Peristalsis, Role of Digestive Enzymes, Bile: Production & Storage, Bile: Function and the Small Intestine: Structure & Adaptations Flashcards

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1
Q

What is the digestive system?

A

The digestive system is an example of an organ system in which several organs work together to digest and absorb food.

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2
Q

Describe digestion

A

Digestion is a process in which relatively large, insoluble molecules in food (such as starch, proteins) are broken down into smaller, soluble molecules that can be absorbed into the bloodstream and delivered to cells in the body
These small soluble molecules (such as glucose and amino acids) are used either to provide cells with energy (via respiration), or with materials with which they can build other molecules to grow, repair and function.

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3
Q

What is the human digestive system made up of? (in general)

A

The human digestive system is made up of the organs that form the alimentary canal and accessory organs

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4
Q

What is the alimentary canal?

A

The alimentary canal is the channel or passage through which food flows through the body, starting at the mouth and ending at the anus.
Digestion occurs within the alimentary canal.

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5
Q

What are accessory organs useful for?

A

Accessory organs produce substances that are needed for digestion to occur (such as enzymes and bile) but food does not pass directly through these organs.

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6
Q

What is the function of the mouth/salivary glands?

A

THE MOUTH IS WHERE MECHANICAL DIGESTION TAKES PLACE
- TEETH CHEW FOOD TO BREAK IT INTO SMALLER PIECES AND INCREASE IT’S SURFACE AREA TO VOLUME RATIO.
AMYLASE ENZYMES IN SALIVA START DIGESTING STARCH INTO
MALTOSE.
THE FOOD IS SHAPED INTO A BOLUS (BALL) BY THE TONGUE AND LUBRICATED IN SALIVA SO IT CAN BE SWALLOWED EASILY.

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7
Q

What is the oesophagus and what is it’s function?

A

TUBE THAT CONNECTS THE MOUTH TO THE STOMACH WHERE THE FOOD BOLUS GOES AFTER BEING SWALLOWED WAVE - LIKE CONTRACTIONS WILL TAKE PLACE TO PUSH THE FOOD BOLUS DOWN WITHOUT RELYING ON GRAVITY.

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8
Q

What is the function of the stomach?

A

FOOD IS MECHANICALLY DIGESTED BY CHURNING ACTIONS WHILE PROTEASE ENZYMES START TO CHEMICALLY DIGEST PROTEINS. HYDROCHLORIC ACID IS PRESENT TO KILL BACTERIA IN FOOD AND PROVIDE THE OPTIMUM PH FOR PROTEASE ENZYMES TO WORK.

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9
Q

What are the parts and functions of the small intestine?

A

FIRST SECTION IS CALLED THE DUODENUM AND IS WHERE THE FOOD COMING OUT OF THE STOMACH FINISHES BEING DIGESTED
BY ENZYMES PRODUCED HERE AND ALSO SECRETED FROM THE PANCREAS
PH OF THE SMALL INTESTINE IS SLIGHTLY ALKALINE - AROUND
PH 8 - 9
SECOND SECTION IS CALLED THE ILEUM AND IS WHERE
ABSORPTION OF DIGESTED FOOD MOLECULES TAKES PLACE
THE ILEUM IS LONG AND LINED WITH VILLI TO INCREASE THE SURFACE AREA OVER WHICH ABSORPTION CAN TAKE PLACE

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10
Q

What is the function of the large intestine?

A

WATER IS ABSORBED FROM REMAINING MATERIAL IN THE COLON
TO PRODUCE FAECES.

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11
Q

What is the function of the anus and rectum?

A

FACES IS STORED IN THE RECTUM AND REMOVED THROUGH THE ANUS

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12
Q

What is the function of the pancreas?

A

PRODUCES ALL THREE TYPES OF DIGESTIVE ENZYME; AMYLASE, PROTEASE AND LIPASE
SECRETES ENZYMES IN AN ALKALINE FLUID INTO THE DUODENUM
FOR DIGESTION TO RAISE PH OF FLUID COMING OUT OF THE STOMACH

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13
Q

What is the function of the liver?

A

PRODUCES BILE TO EMULSIFY FATS (BREAK LARGE DROPLETS
INTO SMALLER DROPLETS) - AN EXAMPLE OF MECHANICAL
DIGESTION
AMINO ACIDS NOT USED TO MAKE PROTEINS BROKEN DOWN HERE (DEAMINATION) WHICH PRODUCES UREA

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14
Q

What are the stages the food goes through during its passage through the alimentary canal?

A

Ingestion, mechanical digestion, chemical digestion, absorption, assimilation and egestion

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15
Q

What is ingestion?

A

Ingestion - the taking in of substances, e.g. food and drink, into the body through the mouth

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16
Q

What is mechanical digestion?

A

Mechanical digestion - the breakdown of food into smaller pieces without chemical change to the food molecules

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17
Q

What is chemical digestion?

A

Chemical digestion - the breakdown of large, insoluble molecules into small, soluble molecules

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18
Q

What is absorption?

A

Absorption - the movement of small food molecules and ions through the wall of the intestine into the blood

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19
Q

What is assimilation?

A

Assimilation - the movement of digested food molecules into the cells of the body where they are used, becoming part of the cells

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20
Q

What is egestion?

A

Egestion - the passing out of food that has not been digested or absorbed (as faeces) through the anus

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21
Q

What is peristalsis?

A

Peristalsis is a mechanism that helps moves food along the alimentary canal.

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22
Q

Describe the process of peristalsis

A

Firstly, muscles in the walls of the oesophagus create waves of contractions which force the bolus along
Once the bolus has reached the stomach, it is churned into a less solid form, called chyme, which continues on to the small intestine

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23
Q

What is produced in peristalsis and why?

A

Mucus is produced to continually lubricate the food mass and reduce friction.

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24
Q

What is needed in peristalsis and why?

A

Dietary fibre as it provides the roughage required for the muscles to push against during peristalsis

25
Q

Describe the function of the circular muscles in peristalsis

A

Circular muscles contract to reduce the diameter of the lumen of the oesophagus or small intestine

26
Q

Describe the function of the longitudinal muscles in peristalsis

A

Longitudinal muscles contract to reduce the length of that section the oesophagus or the small intestine

27
Q

What is it called when the bolus has reached the stomach and is churned into a less solid form?

A

Chyme

28
Q

How is food mechanically digested?

A

By chewing, churning and emulsification

29
Q

Why is food partially digested mechanically?

A

Food is partially digested mechanically (by chewing, churning and emulsification) in order to break large pieces of food into smaller pieces of food which increases the surface area for enzymes to work on

30
Q

Is digestion mainly chemical or mechanical and describe why?

A

Digestion mainly takes place chemically, so that bonds holding the large molecules together are broken to make smaller and smaller molecules

31
Q

Describe chemical digestion

A

Bonds holding the large molecules together are broken to make smaller and smaller molecules. Chemical digestion is controlled by enzymes

32
Q

What are enzymes?

A

Enzymes are biological catalysts – they speed up chemical reactions without themselves being used up or changed in the reaction.

33
Q

What are the three main types of digestive enzymes?

A

There are three main types of digestive enzymes – carbohydrases, proteases and lipases.

34
Q

What are carbohydrases?

A

Carbohydrases are enzymes that break down carbohydrates to simple sugars such as glucose.

35
Q

What is amylase and what does it do?

A

Amylase is a carbohydrase which is made in the salivary glands, the pancreas and the small intestine.
Amylase breaks down starch into maltose. Maltase breaks down maltose into glucose.

36
Q

What are proteases?

A

Proteases are a group of enzymes that break down proteins into amino acids.

37
Q

What is pepsin?

A

Pepsin is an enzyme made in the stomach which breaks down proteins into smaller polypeptide chains.

38
Q

What do Proteases made in the pancreas and small intestine do?

A

Proteases made in the pancreas and small intestine break the peptides into amino acids.

39
Q

What are lipases, where are they produced and secreted?

A

Lipases are enzymes that break down lipids (fats) to glycerol and fatty acids. Lipase enzymes are produced in the pancreas and secreted into the small intestine

40
Q

What is bile and where is it stored?

A

Bile is an alkaline substance produced by cells in the liver
Before being released into the small intestine bile is stored in the gallbladder

41
Q

How does bile emulsify fats?

A

Bile contains bile salts, it is these molecules which emulsify the fats.

42
Q

What are the two main roles of bile and what is the purpose for this?

A

Bile has two main roles:
Neutralising the hydrochloric acid from the stomach and Breaking apart large drops of fat into smaller ones (and so increasing their surface area).

The more alkaline conditions and larger surface area allows lipase to chemically break down the fat (lipids) molecules into glycerol and fatty acids at a faster rate.

43
Q

How does bile neutralise the hydrochloric acid from the stomach and why is it essential?

A

The alkaline properties of bile allow for this to occur.
This neutralisation is essential as enzymes in the small intestine have a higher (more alkaline) optimum pH than those in the stomach.

44
Q

What is emulsification (as a role of bile)?

A

Breaking apart large drops of fat into smaller ones (and so increasing their surface area).

45
Q

What helps lipase to chemically break down the fat (lipids) molecules into glycerol and fatty acids at a faster rate?

A

The more alkaline conditions and larger surface area allows lipase to chemically break down the fat (lipids) molecules into glycerol and fatty acids at a faster rate.

46
Q

What sort of digestion is emulsification and why?

A

Mechanical direction as breaking something into smaller pieces does not break bonds or change the chemical structure of the molecules which make it up.

47
Q

What are the stages of food breakdown?

A

Ingestion
Mechanical digestion
Chemical digestion
Absorption
Assimilation
Egestion

48
Q

What is absorption?

A

Absorption is the movement of small digested food molecules from the digestive system into the blood (glucose and amino acids) and lymph (fatty acids and glycerol).

49
Q

How does the absorption of small molecules occur?

A

Absorption of small soluble molecules occurs through diffusion and sometimes active transport.

50
Q

How is water absorbed in the digestive system?

A

Water is absorbed (by osmosis) primarily in the small intestine, but also in the colon.

51
Q

What occurs after absorption?

A

After absorption, assimilation and egestion occurs

52
Q

What is assimilation?

A

Assimilation is the movement of digested food molecules into the cells of the body where they are used, becoming part of the cells

53
Q

What is egestion?

A

Egestion is the passing out of food that has not been digested or absorbed (as faeces) through the anus.

54
Q

Describe how the small intestine adapted for absorption.

A

The small intestine is adapted for absorption as it is very long and has a highly folded surface with millions of villi (tiny, finger-like projections). These adaptations massively increase the surface area of the small intestine, allowing absorption to take place faster and more efficiently

55
Q

What specific adaptation does the villi of the small intestine have which allows for the rapid absorption of substances?

A

A large surface area, A short diffusion distance, and finally A steep concentration gradient

56
Q

Describe the large surface area crucial for the rapid absorption of substances in the villi of the small intestine?

A

Microvilli on the surface of the villus further increase the surface available for absorption.

57
Q

Describe the short diffusion distance in the villi of the small intestine.

A

The wall of a villus is only one cell thick.

58
Q

Explain the process of the steep concentration gradient in the villi of the small intestine.

A

The villi are well supplied with a network of blood capillaries that transport glucose and amino acids away from the small intestine in the blood. A lacteal (lymph vessel) runs through the centre of the villus to transport fatty acids and glycerol away from the small intestine in the lymph
Enzymes produced in the walls of the villi assist with chemical digestion
The movement of villi helps to move food along and mix it with the enzymes present.
.