HTN MEDS Flashcards
what are indications for thiazide?
HTN, calcium kidney stone, nephrogenic DI
what are S/E for thiazide ?
sulfa allergy, interstitial nephritis, alaklosisw
how does thaizide work and what are the effects?
thaizide works by inhibiting NA/CL transporter of DCT
PLUS CHAND
decrease BP, hypokalemia, hyperuricemia, sulfa allergy, hypercalcemia, metabolic ALKALOSIS, nephritits, hyperglycemia
what does spironolactone and triamterene do?
blocks aldosterone receptors!!! and ENaC receptors
(rememmber hyperaldosteorne is hypokalcemia, akalalosis, htn) so if you BLOCK aldosterone, then the effects youd get is HYPERKACEMIA and ACIDOSIS
so u get decrease pressure, HYPERKALCEMIA, ACIDOSIS
what are some indication for postassium sparing meds?
HTN, HF, hyperaldosterism (since these meds block aldosterone recpetor)
what are S/E of potssaium sparing meds?
HYPERkalzemia, metbaolis ACIDOSIS, gyneomastia (which is why u dont give this to boys)
what are the effects for ACEi/ARBS?
it decreases BP and causes metabolic ACIDOSIS and HYPERkalcemia since were blocking RAAS (which blocks aldoesterone)
what are some indication for ACEi/ARB?
HTN, HR, POST MIw
what are s/e of ACEi/ARB?
HYPERKALCEMIA, METABOLIC ACIDOSIS, COUGH (you get cough with ACEi- crazy right!?)
how does selective B blockers work? Metoprolol, atenolol - VARUN
selective B blocks bind to B1 receptors found in myocaridal muscules
what are the effects for B blockers?
it decreases HR and contractiolity which decrease strain and increases perfusion
what are hte indiciation for selective BB?
HTN w CAD/angina/ACS/MI/postMI
great for compenstated HF since it wiill reduce HF and increase CO
what are the S/E for selective BB? think of varun
impotence, depression, heart block, exercisie intolernace
how do nonselective BB work ? propranolol, labetalol, nadolol
it binds and blocks to B1 adrenergic receptors and B2 AND A1 receptors
what are the effects for non selective BB?
when it binds to B1 and B2 which will reduce HR and contraction and increase perfusion
when it binds to a1 receptor, it will so VASODILATION –> decrease SVR