HTN, Cerebrovascular, Parkinson's, polymyalgia rheu review Flashcards
common form of HTN in the elderly, is defined as sys BP >140 and diastolic BP <90
isolated systolic hypertension
First line pharm therapy for HTN in elderly
thiazide diuretic 12.5 mg
When does SBP more important than DBP as CVD risk factor?
50+
Benefits of lowering BP
decreased stroke, MI, heart failure
Independent risk factor for CVD
LVH
What are thiazides also good for in addition to BP control?
osteopenia/osteoporosis
What are CCBs also good for in addition to BP control?
Raynaud’s syndrome
CI to thiazides
gout or h/o hyponatremia
CI to BBs
2nd/3rd degree heart block
CI in pregnancy for HTN
ACEI/ARB
caused primarily by an increase in arterial stiffness due to increased collagen deposition and cross linking, degeneration of elastin fibers, atherosclerotic changes, and age-related endothelial dysfunction
isolated systolic hypertension
BP readings may be falsely elevated in some elderly patients with very stiff, calcified arteries
pseudohypertension
Two classifications of stroke
ischemic (75%) or hemorrhagic
Brief episodes of focal neurological deficits lasting 2-3 minutes to at most a few hours but no longer than 24 hours leaving no residual deficits with complete functional recovery
TIA
Acute, sustained functional neurological deficit lasting from days to permanent. There is neuronal necrosis or infarction
complete stroke
Small, deep infarcts caused by occlusion of the small arteries that penetrate deeper brain structures. Subtle symptoms
lacunar
stroke present seriously ill. Deteriorate more rapidly and have HA, N/V, and decreased consciousness as prominent signs
hemorrhagic stroke
Rupture of an artery with bleeding onto the surface of the brain
subarachnoid
Cause of subarachnoid hemorrhage
aneursym (85% Berry)
“Worst headache ever” in the patients life radiates to face and neck. Phonophobia or photophobia
subarachnoid hemorrhage
Cause of intracerebral hemorrhage
HTN
Rupture of an artery with bleeding into the brain parenchyma
intracerebral
Treatment of ischemic stroke
fibrinolytic therapy (tPA)
Timeframe for administration of tPA
within 3 hours of onset of signs and symptoms
Characteristics of parkinsons
resting tremor, muscular rigidity, bradykinesia
Initial drug treatment for Parkinsons
carbidopa/levodopa or dopamine agonists
characterised by severe bilateral pain and morning stiffness of the shoulder, neck and pelvic girdle
polymyalgia rheumatica
Most useful lab test for PMR
ESR
Patient presents with new HA, jaw claudication, or visual disturbance. h/o of PMR
giant cell arteritis
Treatment for PMR
prednisone 15mg/day for 18-24 months