HSF II Vascular System Histology Flashcards
blood vascular system consists of
heart and blood vessels
heart
folded endothelial tube
endocardium -> endothelium/ subendothelial CT
myocardium -> syncytium
epicardium -> visceral fibrous pericardium
three myocardium muscles
atrial, ventricular, specialized excit/conduct for muscle fibers
endocardium
endothelium
BM of CT
middle: smooth muscle+elastic ct
subendocardial with purkinje muscle fibers for heart impulse
elastic arteries
lots of elastic tissue in tunica media
maintain BP between sys/diastole
TM thicket
has IEL + EEL
distend in sys/ recoil in diastole
fenestrated elastic sheaths in media, smooth muscle bundles permeating narrow gaps between elastic lamellae
muscular arteries
2-10 mm
more smooth muscle and less elastin in TM
TM thickest
IEL is distinct, EEL sometimes
arterioles
IEL not obvious
major determinants of BP by vasoconstriction/dilation
circular smooth muscle
partial tone (contraction degree)
venous system
tunica media smaller than in arteries
smooth muscle more irregular
have valves
capacitance/reservoir vessels due to distensibility of wall of vessels
foam cells
attempt to resorb cholesterol/fatty patch in damaged walls, but end up secreting things to form a plaque -> when die just leads to more inflammation
atherosclerosis disease process
tm smooth muscle, fibrous CT –> necrosis, secondary CALCIFICATION = hypertension
plaque breaks leads to
clotting cascade leads to thrombus leads to embolus leads to occlusion leads to anoxia and angina
plaque narrowing aka
stenosis
lymphatic vessels conduct
immune cells lymph EC and chylomicrons
lymph node
filter substances with antigenic sampling, recognition, AB production
asymmetrical in tumor metastasis
lack blood, smooth
lymphangions
successive lymph valves