HRT and breast cancer

Question 1

What are the HRT options availabe for women with uterus?

Answer 1

1. Cyclical combined (Estrogen with 12-14 days/ months progesterone)
   or
2. Continous combined - only suiteable if LMP >12 months

Question 2

Name an example of a commonly prescribed combined oral HRT preparation

Answer 2

Estradiol (1 mg) with norethisterone (500 micrograms)

one table once a day - if cyclical norethisterone only added on 12 days

Question 3

Name an example of a commonly combined transdermal HRT formulation

Answer 3

Estradiol 50 microgram per 24 hour, Norethisterone acetate 170 microgram per 24 hour

Usually applied 1-2 weekly (depending on wheather combined or cyclical)