how nerves work 2 Flashcards
resting potential
keeps cells ready to respond
action potential
electrical impulse which is generated along axon
generated potential
defines threshold at which AP is fired.
how is the resting potential maintained?
There is a higher conc. of K+ inside the cell. there is a higher conc. of Na+ outside the cell. there is a higher conc. of cl- outside the cell.
- Maintained by leaky K+ channels which allow K+ to diffuse out of cell.
- Closer to -70mv than -90mv due to other leaky channels( Na+/ Cl-), Na+/K+ pump which pumps 3 Na+ out of cell for every 2 k+ pumped in, large negatively charged molecules which cannot leave the cell
how is K+ concentration maintained in the brain.
astrocytes wrap around the capillaries and lock it tight preventing excess k+ from flowing into the Blood brain barrier and therefore depolarising the cell and causing action potentials to be generated.
the heart unfortunately does not have this so cannot control K+ concentration. this can lead to ventricular fibrillation
equilibrium potential
the potential at which the concentration gradient and the electrical gradient of K+ is equal and opposite.
it depends on what the size of the original potential was.
what is it called when a cell becomes more +ve compared to the RMP?
depolarises
what is it called when a cell becomes more -ve compared to the RMP?
hyperpolarises.