how nerves work 2 Flashcards

1
Q

resting potential

A

keeps cells ready to respond

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2
Q

action potential

A

electrical impulse which is generated along axon

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3
Q

generated potential

A

defines threshold at which AP is fired.

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4
Q

how is the resting potential maintained?

A

There is a higher conc. of K+ inside the cell. there is a higher conc. of Na+ outside the cell. there is a higher conc. of cl- outside the cell.

  • Maintained by leaky K+ channels which allow K+ to diffuse out of cell.
  • Closer to -70mv than -90mv due to other leaky channels( Na+/ Cl-), Na+/K+ pump which pumps 3 Na+ out of cell for every 2 k+ pumped in, large negatively charged molecules which cannot leave the cell
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5
Q

how is K+ concentration maintained in the brain.

A

astrocytes wrap around the capillaries and lock it tight preventing excess k+ from flowing into the Blood brain barrier and therefore depolarising the cell and causing action potentials to be generated.
the heart unfortunately does not have this so cannot control K+ concentration. this can lead to ventricular fibrillation

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6
Q

equilibrium potential

A

the potential at which the concentration gradient and the electrical gradient of K+ is equal and opposite.
it depends on what the size of the original potential was.

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7
Q

what is it called when a cell becomes more +ve compared to the RMP?

A

depolarises

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8
Q

what is it called when a cell becomes more -ve compared to the RMP?

A

hyperpolarises.

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