How it prevents and fights foreign invaders Flashcards
What are the 2 defense systems?
Innate system (everyday military)
Adaptive (special forces)
What do viruses do?
Invade cells and replicate by taking over cellular machinery to create new viruses
Fungi description?
Not a plant or an animal
Break down a hosts cells and absorbs nutrients
Ex: valley fever , athletes foot
Bacteria description
Single celled organism
Release toxins that damage hosts cells
Ex: e-coli, anthrax, pneumonia
Parasites description
Single or multicellular organisms
Extract nutrient from host
Ex: tapeworms
Innate defense description
Present at birth
Respond to ALL foreign substances
First line of defense for innate defense?
Surface barriors
Second line of defense for innate defense?
Internal defenses
Ex: Phagocytes, inflammation, fever
What are the surface barriors for innate defense?
Skin
Respiratory tract
Digestive tract
Genitourinary tract
Skin (innate defense)
Physical barrier
Acidic secretions
Anal and mouth sphincters
Respiratory tract (innate defense)
Mucus
Cilia
Digestive tract (innate defense)
HCL
Digestive enzymes
Genitourinary tract (innate defense)
Acidity of urine
Pussy secretions
What does a non specific defense cell mean?
Means they respond to wide variety of pathogens
All perform phagocytosis
What are the names of the non specific defense cells?
Neutrophils
Eosinophils
Macrophages
Macrophage description
Differenciate from monocytes
Migrate to tissues to clean up pathogens or cell debris
Release interferons
Antimicrobial chemicals
Part of Innate defense
Interferons
Complement proteins
What are interferons?
Proteins released by lymphocytes and macrophages induce viral resistance in healthy cells
What are compliment proteins?
Collection of plasma proteins that create holes in cell membrane
Causes cell to take in water and buuuussstttt
How does a fever start?
Leukocytes secrete pyrogens
Act on hypothalamus to increase body temp lol
Why are fevers effective?
Creates unfavorable environment for pathogens
Stops liver from releasing stuff
Increases metabolic rate of tissue cells for repair
Inflammatory response descriptio
Part of innate defense
Happens when body cells are injured by something physically, chemical irritation, or pathogenic infection
Steps of inflammatory response
- Injury occurs
- Macrophages ingest foreign matter
- Dilation and increased permeability of capillary
- Containment of bacteria and foreign matter
- Luekocyte proliferation and migration
- Continued recruitment of of leukocytes
Step 2 of inflammatory response
Phagocytosis
Macrophages release cytokins to attract more leukocytes