How does meth work in the body? Flashcards
How can meth be taken?
ORALLY
SMOKED
INJECTED
SNORTED
Meth quickly passes the blood-brain barrier. In the brain, it increases levels of dopamine, serotonin (5-HT) and norepinephrine.
How long does it take for meth to reduce effects into the bloodstream?
20-45 minutes
Some of the meth when taken gets absorbed into the bloodstream along the way. What happens to the rest?
Gets filtered out through the liver and kidneys.
In the liver, meth is mainly metabolised to what?
Amphetamine
Meth is well absorbed into the bloodstream after smoking (37.4%) and snorting (79%)
Meth dose elimination in urine
Oral- 30-54% excreted as unchanged meth
10-23% as unchanged amphetamine
Intravenous- 45% is excreted as unchanged meth; 7% as unchanged amphetamine
Meth reaches the bloodstream fairly intact.
As the heart pumps blood through out the body it carries the drug with it.
Mephamphetamine fools the cells into the synapse, causing a surge of exhilaration.