Amphetamine vs Methamphetamine Flashcards

1
Q

The effects of methamphetamine are much stronger typically than amphetamine and they tend to present quickly in comparison to the effects of amphetamine.

A

The effects of methamphetamine are much stronger typically than amphetamine and they tend to present quickly in comparison to the effects of amphetamine.

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2
Q

Methamphetamine breaks down and metabolises into amphetamine (Positive indication in urine tests of high amphetamine excretion).

A

Methamphetamine breaks down and metabolises into amphetamine (Positive indication in urine tests of high amphetamine excretion).

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3
Q

Methamphetamine (METH) generally accepted as more potent and addictive versus Amphetamine (Goodwin, et al., 2009;

A

Methamphetamine (METH) generally accepted as more potent and addictive versus Amphetamine (Goodwin, et al., 2009;

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4
Q

Evidence suggests METH produces a more potent reward signal in the dopamine pathway (Shoblock et al, 2003; Goodwin, et al., 2009)

A

Evidence suggests METH produces a more potent reward signal in the dopamine pathway (Shoblock et al, 2003; Goodwin, et al., 2009)

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5
Q

Peripheral stimulation less pronounced with METH which might explain why users can tolerate higher doses of METH

A

Peripheral stimulation less pronounced with METH which might explain why users can tolerate higher doses of METH

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6
Q

TIME with higher levels of dopamine transportation (Goodwin, et al., 2009)

A

TIME with higher levels of dopamine transportation (Goodwin, et al., 2009)

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7
Q
A
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8
Q

Pharmacodynamic differences: Meth acts primarily on the Nacc regarding DA ; whereas there is more activation in the PFC with Amphetamine use (Shoblock, et al., 2003). Furthermore Glutamate responses are higher in the PFC for Meth versus higher in the Nacc for Amphetamine.

A

Pharmacodynamic differences: Meth acts primarily on the Nacc regarding DA ; whereas there is more activation in the PFC with Amphetamine use (Shoblock, et al., 2003). Furthermore Glutamate responses are higher in the PFC for Meth versus higher in the Nacc for Amphetamine.

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