Host infection interactions Flashcards
CAP presentation
cough, increased sputum, chest pain, dyspnoea, fever, CXR with infiltrates
typical CAP
streptococcus pneumonia,
haemophilus influenza much less
atypical CAP
mycoplasma,
legionella,
chlamydophilia pneumonia,
chlamydia pstiacci,
Pneumonia in immunosupressed
pneumocystis jiroveci,
aspergillus,
TB
CAP Investigation
sputum culture,
viral PCR,
extra (antigen tests, biomarkers)
How can resp. tract infections spread (3)
contact,
airborne (can go long way & linger)
droplet
Cystic fibrosis
staph aureus,
pseudo
…….
HIV pneumonia, often oral candida think -
pneumocystis jirovecii
HIV CD4 <200 pneumonia, often oral candida think -
pneumocystis jirovecii
HIV CD4 count <200
pneumocystis jirovecii,
candida
transplants (& neutropenia) associated with what bug
aspergillus - culture not perfect
risk factors for invasive aspergillosis
cirrhosis, COPD, malignancy, HIV, malnutrition, post-surgical, immunosuppressive
Viruses e.g. influenza A/B, CMV, adenovirus, metapneumovirus, Covid can act as risk factors for invasive aspergillus. T/F?
True
Something that presents similarly to sepsis but is
MIC-s - multisystem inflammatory syndrome
Why are diabetics more likely to ge infection?
decreased T lymphocytes..
,,,