Host Immunity 2 Flashcards
Blood cells are made in the ___
Bone marrow
What happens when stem cells divide?
One daughter cell will remain undifferentiated, while the other will differentiate into a specific cell type
Blood cells have which kind of stem cells?
Hematopoietic
(T/F) Lymphocytes are subsets of WBCs
True!
In innate immunity WBCs can be:
___ (___)
___
___
Phagocytic (macrophage)
Dendritic cells
Neutrophils
Where do macrophage and dendritic cells reside?
In healthy tissues
Long lived cells
Where are neutrophils found?
What do they respond to?
In circulating blood
Chemoattractants (C5a and cytokines)
Phagocytosis will change oxygen into ___ and then
___
Superoxide
Hydrogen peroxide
What does PAMPs stand for?
What are some examples?
What do bind of these receptors trigger?
Pathogen associated molecular patterns
Peptidoglycan, LPS, chitin
Phagocytosis
Phagocytes release cytokines, which does what?
Which communicates with other parts of the immune system
What is an example of direct recognition of pathogens by a phagocyte
PAMPs
Describe the process of indirect recognitions of pathogens by a phagocyte
Phagocytes have receptors that will recognize the complement proteins and will have a different receptor that binds to the antibody protein
What can indirect recognition lead to?
The release of cytokines, which results in a localized response becoming more broad
