hormonii 2 Flashcards
what is activating effect
reversible changes that in the properties of cells
typically induced by hormones that are present onto the cell receptor for a short amount of time
what is organisational effect
a permanent or semi permanent change in the strucutre of the nervous system
change occurs during sensitive periods
the changes happen because steroid hormone - which is able to cross the cell membrance bc its fat solouable and it binds onto a recpetor that is a steroid receptor and enters the cell nuclues where its able to modefy or induce changes in gene activity
what is sexual development
development of sexual organs
and secondaty sexual feautres - breaking of the male voice
sexual identity
changes in the nervous system
how do changes occur
stage 1 - undifferentiated stage
2- sexual differentiation
undifferentiated stage
earlystage that covers the very first weeks of gestation
between fertilisation and week 7
during this point, there is a strucute called gonad which is identical in males and females
gonad will become either ovaries or testies
strucutre has power to develop in either one on the other depending on genetic profile
sxual differentiation stage
at about 7 weeks
gonat becomes ovaries or testies
how does that happen
- organisatinal effects in physical development
y chromsone is a sex determinant gene
makes gonat develop into testies
of y is not present then the gonat becomes an ovary
this is dependent on genetic profile
boys have y chromsone
at abotu 9 weeks of gestation, thre is another key transoframtion
testis produce steroid hormones called androgene - androgene include one hormone claled testosterone
testosteronq
induces or triggers the development of internal and external genitalia in males
also inhibts the development of similar structures in females such that females will develop female genitalia
testoster induces changes in the nervous system
how
testosterone reaches the brain
they hypothalamus
hypothalamus is divided into different parts called nuclei that have different functions
one of this nuclei is sexually dimorphic nuclues - located in an area that is preoptic area
sexually dimorphic nuclues tends to be larger in males
when test reaches the brain, it csn cross the membrance and its chemically transformed into another type of hormone that is estradiol
estradiol can reach the nucleus membrance and reach centre of the cell
this will trigger a no of reactions that achieve the masculinisation of the brain
in females
there is a natural death of sexually dimorphic nuclues which will prevent female brain from being masculinsed
genetic differentiation such that boys have a y chromosme
that will tranform gonat into testies
testies will secrete testosterone
test reaches the brain and triggers masculinisation of the brain
changes occur during sensitive period
a period of maximum sensitivity
specific point in time during which certain changes occur such that they will not result in the same outcome if they were to happen at a different point in time
gonadogenesis sensitive period in pre-natal development
typically starts about week 7 and end about week 9
impact of sexual hormones on physical differences
full development of sexual organs
sex hormones in adolescnce will be accompanied by the appearance of other sexual behaviour