hormones / endocrine organs Flashcards
GnRH causes increases in
FSH and LH
GHRH increases
GH
TRH (thyroid-releasing hormone) produces
TSH
dopamine causes what to decrease
prolactin decreases
ADH and oxytocin is produced in
hypothalamus
released post-pituitary
what does the pancreas produce
insulin
glucagon
somatostatin
insulin generates
beta islets
decreases glucose
glucagon generates
alpha-islets
increases glucose
somatostatin generates
delta islets
decreases insulin and glucagon
glucagon is
the stored form of sugar
gonads produce
testosterone in testes
estrogen and progesterone in ovaries
pineal gland produces
melatonin
regulated circadian rhythm
anterior pituitary generates
note: FLAT PEG
FSH
LH
ACTH
TSH
Prolactin
Endorphins
GH
“FLAT PEG”
FSH is responsible for
male spermatogenesis
female ovarian follicle growth
LH generates
testosterone
induces ovulation
ACTH makes and releases
glucocorticoids from adrenal cortex
TSH makes and releases
triiodothyronine and thyroxine (T3 and T4)
from thyroid
prolactin causes increase in
milk
endorphins decrease
pain
GH causes increases in
growth in bone/muscle
glucose in bone/muscle
thyroid gland makes
T4 and T3
made by follicle cells
increase basal metabolic rate
what makes calcitonin
parafollicular (c) cells in thyroid
calcitonin causes Ca2+ increase/decrease in…
Ca2+ increase in bone and excretion from kidneys
Ca2+ decrease in blood and gut
parathyroid glands generate
PTH
PTH causes what to increase and decrease
Ca2+ increase in blood and absorption in gut
Ca2+ decrease in bone and excretion in kidney
PTH activates
vitamin D in kidney
bone breakdown releases
Ca2+
posterior pituitary pathway releases
ADH
oxytocin
ADH causes decrease in
water output in urine
oxytocin causes increase in
urine concentration / milk / bonding behavior
positive feedback
adrenal cortex produces
glucocorticoids
mineralocorticoids
androgens
glucocorticoids produces
cortisol and cortisone
glucocorticoids causes what to increase and decrease
glucose increase
protein synthesis and immune system decrease
mineralocorticoids produces
aldosterone
mineralcorticoids causes increase/decrease in
K+ and BP decrease
Na+ and water increase
androgens convert to
testosterone and estrogen in the gonads
adrenal medulla produce
catecholamines
hormones made by adrenal medulla
epinephrine (anti-histamine)
norepinephrine
epinephrine causes increase in
heart rate and BP
norepinephrine causes increase in
heart rate and BP
GHRH (growth hormone-releasing hormone) stimulates
anterior pituitary to release GH
what produces GHRH?
hypothalamus
anterior pituitary regulates
stress, growth, reproduction, lactation
GnRH stimulates
anterior pituitary
GnRH stimulates anterior pituitary to release
FSH and LH
what produces GnRH
hypothalamus
TRH stimulates
anterior pituitary to release TSH
TRH is produced by
hypothalamus
growth hormone stimulates
growth and cell reproduction
growth hormone is release by
anterior pituitary
oxytocin and ADH are released by
posterior pituitary
posterior pituitary is the
posterior lobe of the pituitary gland
what acts on endocrine glands
tropic hormones
tropic hormones induce
endo glands to secrete other hormones
e.g. GnRH –> LH
ADH causes increase/decrease in
BP and H20 retention increase
decrease plasma osmolarity
ADH is produced by
hypothalamus
release by posterior pituitary
peptide hormone consists of
AAs
water-soluble
peptide hormones examples
insulin
glucagon
leptin
ADH
oxytocin
TSH stimulates
thyroid to release t4 and t3
TSH is released from
anterior pituitary
CRH (corticotropin releasing hormone) stimulates
anterior pituitary to release ACTH
CRH is produced by the
hypothalamus
ACTH stands for
adrenocorticotropic hormone (released from adrenal cortex)
prolactin-release inhibitng factor is aka
dopamine
dopamine is a
neurohormone
what is dopamine in the brain
neurotransmitter
in the endocrine system, what does dopamine do
regulate hormone release
dopamine inhibits
prolactin release from anterior pituitary
oxytocin stimulates
uterine contractions and breast milk production
oxytocin is produced in the
hypothalamus
what releases oxytocin
posterior pituitary
FSH is released from
anterior pituitary
FSH in males
triggers spermatogenesis
stimulates sertoli cells
FSH in females
ovarian follicle development
LH is released from the
anterior pituitary
LH surge occurs during
2 most fertile days (includes ovulation day)
where is ACTH released from
anterior pituitary
ACTH stimulates production and release of
cortisol
catecholamines target
adergenic receptors (GCPR)
examples of catecholamines
norepinephrine
epipinehrine
3 major classes of hormones
peptides
amino
steroid hormones
polypeptides
proteins + peptides
water soluble
amines are derived from
AAs
water and lipid soluble
are steroid hormones lipid or water soluble
lipid soluble
what are steroid hormones derived from
lipids
examples of steroid hormones
esterogen
progesterone
testoterone
direct hormones act directly on the
target tissue/organ
e.g. insulin
GHIH is aka
somatostatin
hypothalamus is located:
below the thalamus
pancreas is a
large gland behind stomach
pancreas secretes
digestive enzymes into duodenum
islets of Langerhands secretes
insulin and glucagon
embedded in the pancreas
gonads are a gland that produces
gametes (sex cells) and sex hormones
pineal gland is located in the
epithalamus, tucked into a groove between the two thalamus halves
adrenal cortex sits along the
perimeter of the adrenal gland (top of kidney)
mediates stress response
ADH (vasopressin) regulated the
tonicity of body fluids
ADH is released in response to
hypertonicity and causes the kidneys to reabsorb water
ADH release results in
concentrated urine and reduced urine volume
increases BP
oxytocin is what kind of hormone
peptide
oxytocin is synthesized in the
hypothalamus and released by the posterior pituitary
t4 and t3 are created from
iodine and tyrosine
during childbirth, oxytocin increases
uterine contractions and is released in response to cervix stretching
also increases milk production + certain bonding behaviors
t4 is a precursor to
t3
thyroid gland are in the
neck and below the adam’s apple
thyroid secretes
thyroid hormones that regulate metabolism
thyroid helps regulates (what) homeostasis
calcium
parathyroid glands are located on the
back of the thyroid
parathyroid function
maintain body’s Ca2+ and K+ so that nervous and muscular systems function properly
adrenal medulla sits on top of the
kidney
at the center of adrenal gland surrounded by the adrenal cortex
adrenal medulla converts
tyrosine into catecholamines