Hormones Flashcards
Function and pathways
GnRH
Released by hypothalamus –> Anterior Pituitary –> LH and FSH
GHRH (Growth Releasing Hormone)
Released by hypothalamus –> Anterior Pituitary –> Growth Hormone –> influences bones, muscles, and increased glucose levels
TRH (Thyroid Releasing Hormone)
Hypothalamus –> Anterior Pituitary –> TSH –> Thyroid –> T3 and T4 –> blood and small intestine
CRH (Corticotropin Releasing Hormone)
Hypothalamus –> Anterior Pituitary –> ACTH –> Adrenal Cortex –> Glucocorticoids like Cortisol
PIF (Prolactin Inhibiting Factor)
Hypothalamus –> Anterior Pituitary –> inhibits prolactin release
FSH (Follicle Stimulating Hormone)
FLAT PEG: AP
- peptide hormone
- follicle maturation in females/ spermatogenesis in males
Leutinizing Hormone (LH)
FLAT PEG: AP
- peptide hormone
- ovulation in females/testosterone synthesis in males
Growth Hormone (GH)
FLAT PEG: AP
- peptide hormone
- influences muscles and bones, increases blood glucose
Thyroid-Stimulating Hormone (TSH)
FLAT PEG: AP
- peptide hormone
- influences thyroid to release T3 and T4
Adrenocorticotropic Hormone (ACTH)
FLAT PEG: AP
- peptide hormone
- influences adrenal cortex to release glucocorticoids like cortisol
Prolactin
FLAT PEG: AP
- peptide
- influences milk production and secretion in breasts
- inhibited by Prolactin Inhibiting Factor released by hypothalamus (PIF)
Endorphins
FLAT PEG: AP
- peptide hormone
- decrease pain sensation, increase euphoria
Antidieuretic Hormone (ADH)
PP
- peptide hormone
- increases water reabsorption by increasing permeability of the collecting duct
- acts in response to increased blood osmolarity and decreases blood osmolarity
- increases blood volume and bp
Oxytocin
PP
- peptide hormone
- uteral contractions, pleasure feelings, bonding
Calcitonin
Thyroid Cells
- amino acid hormone
- decreases blood calcium levels by inhibiting the action of osteoclasts on bones
Parathyroid Hormone
Parathyroid
- amino acid hormone
- increases blood calcium levels by promoting action of osteoclasts on bones
Glucagon
Pancreas: PIGS (alpha cells)
- peptide
- raises blood glucose levels by breaking down glycogen and inhibits protein production
- promotes glyconeogenesis
- releases fatty acids from adipose cells into blood stream
Insulin
Pancreas: PIGS (beta cells)
- peptide
- lowers blood glucose levels storing glucose as glycogen
Somatostatin
Pancreas: PIGS (delta cells)
- peptide
- inhibits both insulin and glucagon
Aldosterone
Adrenal Cortex: SSS
- mineralocorticoid steroid
- in response to Angiotensin II
- increases sodium reabsorption in the distal convoluted tubule and collecting duct –> results in pulling water into the blood stream –> increases blood volume and blood pressure
- does NOT change blood osmolarity
- increases K+ and H+ excretion
Estrogen
Adrenal Cortex: SSS
- steroid
- development of female secondary sexual characteristics; maturation of sperm in males
Progesterone
Adrenal Cortex: SSS
- steroid
- influences periods: after ovulation, increases in preparation for embryo implantation, when embryo does not implant results in decrease and shedding of uterine lining
Testosterone
Adrenal Cortex: SSS
- steroid
- male secondary sexual characteristics and development of testes and prostate
Epinephrine
Adrenal Medulla: MEN
- peptide
- promotes glycogenolysis in liver to increases blood sugar
- promotes glycogenolysis in muscles to increase blood sugar