Hormones Flashcards
5 hormone signals:
- Chemical synthesis/release
- Survival (stay low key)
- Proliferate
- Differentiate
- Apoptosis
Fat soluble hormones
Steroids derived from lipids [cholesterol], estrogen, testosterone, progesterone
-Able to cross cell membrane and bind to internal receptors
Water soluble hormones
Amino acids - made of short chains
Polypeptides - long chains of amino acids
NOT able to cross cell membrane, relies on receptors to work
Hypothalamic-Pituitary-Gonadal Axis
The hypothalamus (GnRH), pituitary gland (FSH and LH), and gonadal glands (inhibin), collectively. Connection between nervous and endocrine system.
(Anterior) Pituitary Gland
“Master” endocrine gland. Receives signal from hypothalamus and secretes FSH (follicle stimulating hormone) and LH (Luteinizing Hormone)
Hypothalamus
Releases Gonadotropin-releasing factor (GnRH) which is received by the anterior pituitary gland.
FSH
Follicle stimulating hormone.
In males, affects spermatogenesis and sertoli cells. Ihnibits LH.
In females, important for maintaining the survival of follicles.
LH
Leuteinizing hormone.
In males, acts on leydig cells to aid in testosterone production.
In females, important for estrogen production.
5DHT
Steroid vital for full closure of the scrotal sac (hypospadia).
Estradiol
Steroid found in leydig cells that maintain bone density and help w/ maturation of sperm in epididymis in men, and developing follicle in women.
Progesterone
Steroid secreted by the granulosa cells after ovulation. Mature follicle releases oocyte and post ovulation granulosa cell becomes an endocrine organ which releases progetserone (corpus luteum).