hormones Flashcards
hormone
-hormones are chemical substances produced by glands, which are carried by the blood, which alters the activity of one or more specific target organs and is destroyed by the liver
anti-diuretic hormone
-endocrine gland - hypothalamus produces ADH, pituitary gland stores and releases ADH
-function - osmoregulation
-target organs - walls of collecting duct
insulin and glucagon (secreted directly into bloodstream)
-endocrine gland - islets of langerhans in pancreas
-function - blood glucose regulation
-target organs - insulin is liver and muscle cells, glucagon is liver cells only
adrenaline
-endocrine gland - adrenal glands
-function - produced under situations of fear, stress, anger, anxiety
-target organs - heart, lungs, pupils of eyes
oestrogen and progesterone
-endocrine gland - ovaries
-function - regulation of menstrual cycle
-target organs - uterine lining/ endometrium
higher blood glucose above norm
-islets of langerhans of pancreas is stimulated
-insulin is secreted by the islets of langerhans
-signals liver and muscle cells to convert excess glucose to glycogen for storage
-increases permeability of cell membrane to glucose which increases uptake of glucose into cells
-the concentration of glucose in the blood is reduced back to norm
lower blood glucose below norm
-islets of langerhans of pancreas stimulated
-glucagon is secreted by islets of langerhans
-signals liver cells to convert glycogen back to glucose, which is then released into bloodstream
-blood glucose concentration is raised back to norm
type 1 diabetes
-islets of langerhans of pancreas produces insufficient insulin
-beta cells that produce insulin are destroyed by autoimmune disease
-tends to develop during childhood
-requires insulin injections to replace missing hormone
type 2 diabetes
-islets of langerhans of pancreas produces insulin
-target cells do not respond to insulin production, caused by the down-regulation of insulin receptors on target cells
-tends to develop during adulthood
-controlled by managing diet and lifestyle
immediately after a meal,
-glucose cannot be stored in the liver and muscles as glycogen, thus blood glucose levels remain high
-blood glucose concentration can reach a level that exceeds the kidney’s ability to completely reabsorb all the glucose
-the glucose that is not reabsorbed is excreted in the urine
after a period of dieting/ starving,
-the body oxidises fats instead of glucose to release energy
-results in the production of ketones which are excreted in urine
long term effects of diabetes mellitus
-increased risk of coronary heart disease, kidney failure, blindness
adrenaline and target organs
liver and muscle
-increased conversion of stored glycogen to glucose
-glucose is needed for respiration which releases energy
heart
-increased heart rate
-increased volume of blood pumped per unit time, increasing glucose and oxygen supply to muscle for respiration
lungs
-increased breathing rate
-increased absorption of oxygen, which is needed for respiration
brain
-increased blood flow to the brain
-brain can think more clearly
muscle
-increased blood flow to the muscle
-blood contains oxygen and glucose can reach muscles, where aerobic respiration occurs
eyes
-dilation of pupils
-allows more light to enter the eyes for enhanced vision
digestive system, kidneys, skin
-decreased blood flow
-more blood can be transported to brain and muscles