Hormonal communication and the adrenal glands Flashcards
What is the endocrine system?
uses hormones to send info about changes in the environment around the body to bring about responce
What does the endocrine system consist of?
endocrine glands that secrete hormones directly into the bloodstream
What is the role of hormones?
serve as chemical messengers binding to specific receptors on target cells
What are target cells?
cells that have specific receptors for a hormone, once the hormone binds to the receptors it stimulates the target cells to produce a responce
How do hormones act as chemical messengers?
1) hormones produced by endocrine gland cells
2) when stimulated glands release hormones into the bloodstream
3) blood carries hormones to their target cells
4) they attach to receptors on or in the target cell
5) the cells then respond to thehormones
What are non-steroidal hormones?
- water soluble (hydrophilic)
- can’t diffuse across phospholipid bilayer
- bind to receptors on cell surface membrane of their target cells to activate second messengers
What are examples of non steroidal hormones?
- adrenaline
- noradrenaline
What are steroidal hormones?
- lipid soluble (hydrophobic)
- can diffuse across the phospholipid bilayer
- bind to receptor molecules in the cytoplasm or nucleus, forming a hormone-receptor complex acting as a transcription factor
What are examples of steroidal hormones?
- oestrogen
What maintains homeostasis?
- endocrine system
- nervous system
What are the features of the endocrine system?
- signaled through hormones
- transmission by blood flow
- slow transmission speed
- widespread spread
- long duration of effect
What are features of the nervous system?
- signalled through nerve impulses
- transmission by neurons
- rapid transmission speed
- localised spread
- short duration of effect
What is the location and structure of the adrenal glands?
- triangular endocrine glands located above each kidney
- consists of 2 main regions surrounded by a capsule
What are the 2 main regions of the adrenal glands?
Adrenal cortex = outer region of the glands responsible for producing vital steroid hormones
Adrenal medulla = inner region at the center of the glands known for producing non-steroidal hormones
What is the function of glucocorticoids and give an example?
Function = regulate metabolism, controls blood pressure and stress response and suppresses inflammation
E.g = cortisol and corticosterone
What is the function of mineralocorticoids and give an example?
Function = maintain blood pressure by balancing salt and water in the blood and body fluids
E.g = aldosterone
What is the function of androgens and give an example?
Function = regulation of sexual characteristics and cell growth
E.g testosterone
How is the release of hormones from the adrenal cortex regulated?
regulated by chemical signals from the hypothalamus and kidneys
What does the adrenal medulla produce and when?
Produces = catecholamines (non steroidal hormones)
When = prepare the body for stressful or dangerous situations when the body’s stimulated by the SNS
What are the main affects of adrenaline?
- dilated bronchioles
- increased BR
- increased blood glucose levels
- increased HR and BP increasing blood flow to the muscles and brain
What are the main affects of noradrenaline?
- increased HR
- expands air passages
- dilates pupils
- vasoconstriction of non-essential organs