Hormonal anti-cancer agents Flashcards
1
Q
Abiraterone
A
Antiandrogen (irreversibly inhibits CYP17)
2
Q
Letrozole
A
Aromatase inhibitor
3
Q
Leuprolide
A
GnRH agonist
4
Q
Bicalutamide
A
Antiandrogen (partial androgen antagonist)
6
Q
Exemestane
A
Aromatase inhibitor
8
Q
Goserelin
A
GnRH agonist
9
Q
Histrelin
A
RnRH agonist
10
Q
Enzalutamide
A
Antiandrogen (androgen receptor antagonist)
11
Q
Tamoxifen
A
anti-estrogen (SERM)
+ in bone and uterus
- in breast
12
Q
Flutamide
A
Antiandrogen (partial androgen antagonist)
13
Q
Raloxifen
A
anti-estrogen (SERM)
+ in bone
- in breast
No effect in uterus
14
Q
Fulvestrant
A
Anti-estrogen (pure antagonist)
15
Q
Anastrazole
A
Aromatase inhibitor
16
Q
Nilutamide
A
Antiandrogen (partial androgen antagonist)
19
Q
Toremifene
A
anti-estrogen (SERM)
+ in bone and uterus
- in breast
